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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPB1 All Species: 36.36
Human Site: S653 Identified Species: 61.54
UniProt: P53618 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53618 NP_001137533.1 953 107142 S653 K L E E E K L S Q K K E S E K
Chimpanzee Pan troglodytes XP_001172023 953 107170 S653 K L E E E K L S Q K K E S E K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534069 1054 117865 S754 K L E E E K L S Q K K E S E K
Cat Felis silvestris
Mouse Mus musculus Q9JIF7 953 107048 S653 K L E E E K L S Q K K E S E K
Rat Rattus norvegicus P23514 953 106992 S653 K L E E E K L S Q K K E S E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507656 953 106948 S653 K L E E E K L S Q K K E S E K
Chicken Gallus gallus Q5ZIA5 953 107103 S653 K L E E E K L S Q K K E S E K
Frog Xenopus laevis NP_001090083 953 106905 S653 K L E E E K L S Q K K E S E K
Zebra Danio Brachydanio rerio NP_001002013 953 107075 S653 R L E E E K L S Q K K E S E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45437 964 107388 L666 H D E D Q R M L K E K Q K A T
Honey Bee Apis mellifera XP_001120953 949 104712 N644 K A E E D S Q N Q K A K E K P
Nematode Worm Caenorhab. elegans NP_494441 971 107512 A662 D V T T E K M A S T T A A G Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SV20 948 106059 E654 I S E K Q L R E M E E L K A K
Baker's Yeast Sacchar. cerevisiae P41810 973 109001 H670 E I A K K N K H K R A L K D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 89.6 N.A. 99.2 99 N.A. 97.5 97.9 94.7 93.4 N.A. 67.1 69.7 60.1 N.A.
Protein Similarity: 100 99.7 N.A. 90.1 N.A. 99.7 99.7 N.A. 99.1 99.3 98.1 96.9 N.A. 81.1 82.6 75.8 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 13.3 33.3 13.3 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 60 60 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.2 42.5 N.A.
Protein Similarity: N.A. N.A. N.A. 70.3 64.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 8 0 0 15 8 8 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 8 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 8 0 86 72 72 0 0 8 0 15 8 65 8 65 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 65 0 0 15 8 72 8 0 15 72 72 8 22 8 72 % K
% Leu: 0 65 0 0 0 8 65 8 0 0 0 15 0 0 0 % L
% Met: 0 0 0 0 0 0 15 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 15 0 8 0 72 0 0 8 0 0 0 % Q
% Arg: 8 0 0 0 0 8 8 0 0 8 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 8 0 65 8 0 0 0 65 0 8 % S
% Thr: 0 0 8 8 0 0 0 0 0 8 8 0 0 0 8 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _