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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPB1 All Species: 31.21
Human Site: S37 Identified Species: 52.82
UniProt: P53618 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53618 NP_001137533.1 953 107142 S37 L E K G D V K S K T E A L K K
Chimpanzee Pan troglodytes XP_001172023 953 107170 S37 L E K G D V K S K T E A L K K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534069 1054 117865 S138 L E K G D V K S K T E A L K K
Cat Felis silvestris
Mouse Mus musculus Q9JIF7 953 107048 S37 L E K G D V K S K T E A L K K
Rat Rattus norvegicus P23514 953 106992 S37 L E K G D V K S K T E A L K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507656 953 106948 S37 L E K G D V K S K T E A L K K
Chicken Gallus gallus Q5ZIA5 953 107103 L37 L E K G D V K L K T E A L K K
Frog Xenopus laevis NP_001090083 953 106905 S37 L E K G D V K S K T E A L K K
Zebra Danio Brachydanio rerio NP_001002013 953 107075 A37 L E K G E I K A K T E A L K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45437 964 107388 I37 K G D T N V K I E T L K R V I
Honey Bee Apis mellifera XP_001120953 949 104712 T38 L E K G D V H T K I E A L K K
Nematode Worm Caenorhab. elegans NP_494441 971 107512 E37 F E K G G D K E R I E A L K K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SV20 948 106059 A37 D V E A K V D A M K K A I M L
Baker's Yeast Sacchar. cerevisiae P41810 973 109001 Q39 L E K G S D E Q K I D T M K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 89.6 N.A. 99.2 99 N.A. 97.5 97.9 94.7 93.4 N.A. 67.1 69.7 60.1 N.A.
Protein Similarity: 100 99.7 N.A. 90.1 N.A. 99.7 99.7 N.A. 99.1 99.3 98.1 96.9 N.A. 81.1 82.6 75.8 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 93.3 100 80 N.A. 20 80 60 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 93.3 100 100 N.A. 33.3 86.6 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.2 42.5 N.A.
Protein Similarity: N.A. N.A. N.A. 70.3 64.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 15 0 0 0 86 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 65 15 8 0 0 0 8 0 0 0 0 % D
% Glu: 0 86 8 0 8 0 8 8 8 0 79 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 86 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 8 0 22 0 0 8 0 8 % I
% Lys: 8 0 86 0 8 0 79 0 79 8 8 8 0 86 79 % K
% Leu: 79 0 0 0 0 0 0 8 0 0 8 0 79 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 8 8 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % R
% Ser: 0 0 0 0 8 0 0 50 0 0 0 0 0 0 8 % S
% Thr: 0 0 0 8 0 0 0 8 0 72 0 8 0 0 0 % T
% Val: 0 8 0 0 0 79 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _