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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METAP1
All Species:
36.36
Human Site:
S33
Identified Species:
61.54
UniProt:
P53582
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53582
NP_055958.2
386
43215
S33
I
K
L
G
I
Q
G
S
Y
F
C
S
Q
E
C
Chimpanzee
Pan troglodytes
XP_001165908
367
40994
S33
I
K
L
G
I
Q
G
S
Y
F
C
S
Q
E
C
Rhesus Macaque
Macaca mulatta
XP_001099172
464
51572
S111
I
K
L
G
I
Q
G
S
Y
F
C
S
Q
E
C
Dog
Lupus familis
XP_544993
353
39779
S33
K
A
K
R
E
V
S
S
W
T
V
E
G
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BP48
386
43203
S33
I
K
L
G
I
Q
G
S
Y
F
C
S
Q
E
C
Rat
Rattus norvegicus
NP_001099946
386
43187
S33
I
K
L
G
I
Q
G
S
Y
F
C
S
Q
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIM5
385
43103
S33
L
K
L
G
I
Q
G
S
Y
F
C
S
Q
E
C
Frog
Xenopus laevis
Q7ZWV9
385
43178
S33
I
K
L
G
I
Q
G
S
Y
F
C
S
Q
E
C
Zebra Danio
Brachydanio rerio
Q4QRK0
386
43548
S33
I
K
L
G
I
Q
G
S
Y
F
C
S
Q
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651281
374
41708
S33
I
K
G
S
F
F
C
S
Q
P
C
F
K
G
F
Honey Bee
Apis mellifera
XP_393865
377
42283
T36
I
Q
G
S
Y
F
C
T
Q
D
C
F
K
R
S
Nematode Worm
Caenorhab. elegans
NP_500396
371
41724
F33
M
S
L
P
D
A
Y
F
C
D
Q
S
C
F
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SLN5
398
43974
A39
L
K
L
P
R
E
Q
A
S
F
C
T
Q
E
C
Baker's Yeast
Sacchar. cerevisiae
Q01662
387
43355
S33
Q
C
G
R
E
T
S
S
Q
M
K
C
P
V
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
82.7
90.1
N.A.
98.1
97.9
N.A.
N.A.
94.8
88
86.7
N.A.
61.6
66.3
60.3
N.A.
Protein Similarity:
100
95
83.1
91.1
N.A.
99.4
99.4
N.A.
N.A.
97.9
95
93.7
N.A.
75.1
79.5
72
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
93.3
100
100
N.A.
26.6
13.3
13.3
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
33.3
33.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.7
47.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.1
62.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
15
0
8
0
79
8
8
0
72
% C
% Asp:
0
0
0
0
8
0
0
0
0
15
0
0
0
8
0
% D
% Glu:
0
0
0
0
15
8
0
0
0
0
0
8
0
65
0
% E
% Phe:
0
0
0
0
8
15
0
8
0
65
0
15
0
8
8
% F
% Gly:
0
0
22
58
0
0
58
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
65
0
0
0
58
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
72
8
0
0
0
0
0
0
0
8
0
15
0
8
% K
% Leu:
15
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
15
0
0
0
0
0
8
0
0
8
0
0
% P
% Gln:
8
8
0
0
0
58
8
0
22
0
8
0
65
0
0
% Q
% Arg:
0
0
0
15
8
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
0
15
0
0
15
79
8
0
0
65
0
0
8
% S
% Thr:
0
0
0
0
0
8
0
8
0
8
0
8
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
58
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _