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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAPK1
All Species:
24.24
Human Site:
Y1421
Identified Species:
53.33
UniProt:
P53355
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53355
NP_004929.2
1430
160073
Y1421
S
C
N
S
G
T
S
Y
N
S
I
S
S
V
V
Chimpanzee
Pan troglodytes
XP_001140200
1430
160025
Y1421
S
C
N
S
G
T
S
Y
N
S
I
S
S
V
V
Rhesus Macaque
Macaca mulatta
XP_001084634
1430
160024
Y1421
S
C
N
S
G
T
S
Y
N
S
I
S
S
V
V
Dog
Lupus familis
XP_541259
1430
159848
Y1421
S
C
N
S
G
T
S
Y
N
S
I
S
S
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80YE7
1442
161423
Y1421
S
C
N
S
G
T
S
Y
N
S
I
S
S
V
V
Rat
Rattus norvegicus
O88764
448
51431
R440
V
R
A
L
E
Q
E
R
L
Q
A
E
C
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026784
974
109076
V966
V
S
N
I
N
G
R
V
C
A
S
Q
N
V
I
Frog
Xenopus laevis
NP_001086727
1427
159871
Y1418
S
C
N
S
G
T
S
Y
N
S
I
S
S
V
V
Zebra Danio
Brachydanio rerio
NP_001093460
1439
159594
G1427
S
P
V
C
N
G
G
G
T
S
Y
N
S
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490840
1425
158950
S1416
G
V
V
S
S
C
H
S
S
S
E
H
N
P
I
Sea Urchin
Strong. purpuratus
XP_780774
1084
119703
H1076
Q
S
G
S
G
S
N
H
S
S
G
T
V
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.3
95.5
N.A.
94.3
24.2
N.A.
N.A.
60.7
86
74.7
N.A.
N.A.
N.A.
34.5
29.5
Protein Similarity:
100
99.9
99.7
97.9
N.A.
97.5
28.8
N.A.
N.A.
65.8
93.8
87.2
N.A.
N.A.
N.A.
54.4
45.9
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
13.3
100
20
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
33.3
100
33.3
N.A.
N.A.
N.A.
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
10
10
0
0
10
0
% A
% Cys:
0
55
0
10
0
10
0
0
10
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
0
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
64
19
10
10
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
55
0
0
10
19
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
64
0
19
0
10
0
55
0
0
10
19
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
10
0
0
0
0
10
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
10
10
0
0
0
0
0
0
0
% R
% Ser:
64
19
0
73
10
10
55
10
19
82
10
55
64
0
19
% S
% Thr:
0
0
0
0
0
55
0
0
10
0
0
10
0
0
0
% T
% Val:
19
10
19
0
0
0
0
10
0
0
0
0
10
64
64
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _