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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAPK1 All Species: 19.39
Human Site: S745 Identified Species: 42.67
UniProt: P53355 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53355 NP_004929.2 1430 160073 S745 S K P T V S V S I N N L Y P G
Chimpanzee Pan troglodytes XP_001140200 1430 160025 S745 S K P T V S V S I N N L Y P G
Rhesus Macaque Macaca mulatta XP_001084634 1430 160024 S745 S K P T V S V S I N N L Y P G
Dog Lupus familis XP_541259 1430 159848 S745 S K P A V S V S I S N L Y P G
Cat Felis silvestris
Mouse Mus musculus Q80YE7 1442 161423 S745 A K P T V S V S I N N L Y P G
Rat Rattus norvegicus O88764 448 51431
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026784 974 109076 G359 I N D D N V P G L Q H L L G S
Frog Xenopus laevis NP_001086727 1427 159871 I745 A K T V S V S I S D L Y P G C
Zebra Danio Brachydanio rerio NP_001093460 1439 159594 S745 P A V S V S I S N L Y P G C E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_490840 1425 158950 D740 S V T R R I S D H Y S P S S S
Sea Urchin Strong. purpuratus XP_780774 1084 119703 D468 G T I P G A G D F T F L E F S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.3 95.5 N.A. 94.3 24.2 N.A. N.A. 60.7 86 74.7 N.A. N.A. N.A. 34.5 29.5
Protein Similarity: 100 99.9 99.7 97.9 N.A. 97.5 28.8 N.A. N.A. 65.8 93.8 87.2 N.A. N.A. N.A. 54.4 45.9
P-Site Identity: 100 100 100 86.6 N.A. 93.3 0 N.A. N.A. 6.6 6.6 20 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 0 N.A. N.A. 20 20 33.3 N.A. N.A. N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 10 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % C
% Asp: 0 0 10 10 0 0 0 19 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 10 0 0 10 0 % F
% Gly: 10 0 0 0 10 0 10 10 0 0 0 0 10 19 46 % G
% His: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % H
% Ile: 10 0 10 0 0 10 10 10 46 0 0 0 0 0 0 % I
% Lys: 0 55 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 10 10 64 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 0 0 0 10 37 46 0 0 0 0 % N
% Pro: 10 0 46 10 0 0 10 0 0 0 0 19 10 46 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 46 0 0 10 10 55 19 55 10 10 10 0 10 10 28 % S
% Thr: 0 10 19 37 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 0 10 10 10 55 19 46 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 10 10 46 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _