KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-5
All Species:
20.61
Human Site:
Y97
Identified Species:
41.21
UniProt:
P52952
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52952
NP_004378.1
324
34918
Y97
P
A
F
Y
P
R
A
Y
S
D
P
D
P
A
K
Chimpanzee
Pan troglodytes
XP_518104
325
35024
Y97
P
A
F
Y
P
R
A
Y
S
D
P
D
P
A
K
Rhesus Macaque
Macaca mulatta
XP_001096796
324
34944
Y97
P
A
F
Y
P
R
A
Y
S
D
P
D
P
A
K
Dog
Lupus familis
XP_543239
342
36276
D98
N
H
Q
T
S
L
V
D
T
A
P
L
I
C
P
Cat
Felis silvestris
Mouse
Mus musculus
P42582
318
34144
Y96
P
T
F
Y
P
G
A
Y
G
D
P
D
P
A
K
Rat
Rattus norvegicus
O35767
318
34318
Y96
P
T
F
Y
P
R
A
Y
G
D
P
D
P
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
D90
T
A
K
D
S
K
A
D
K
K
E
L
C
A
L
Frog
Xenopus laevis
P42583
299
34079
K90
N
Y
L
E
M
D
S
K
D
P
K
D
H
K
K
Zebra Danio
Brachydanio rerio
Q90481
269
30288
Y84
A
T
T
D
S
I
Q
Y
S
L
H
G
L
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015473
468
50968
A213
T
A
N
D
P
R
F
A
I
S
R
L
M
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
Y97
P
G
R
L
P
G
N
Y
F
A
G
P
F
P
G
Sea Urchin
Strong. purpuratus
XP_783123
344
37966
T120
C
S
F
H
P
D
T
T
G
D
I
N
I
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.8
40
N.A.
87.6
85.8
N.A.
N.A.
66.6
62.3
32.4
N.A.
26.9
N.A.
29.3
35.1
Protein Similarity:
100
99.3
97.8
49.7
N.A.
91.3
89.5
N.A.
N.A.
76.8
73.7
43.8
N.A.
40.5
N.A.
42.2
49.7
P-Site Identity:
100
100
100
6.6
N.A.
80
86.6
N.A.
N.A.
20
13.3
13.3
N.A.
20
N.A.
20
20
P-Site Similarity:
100
100
100
13.3
N.A.
80
86.6
N.A.
N.A.
26.6
20
20
N.A.
26.6
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
42
0
0
0
0
50
9
0
17
0
0
0
50
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% C
% Asp:
0
0
0
25
0
17
0
17
9
50
0
50
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% E
% Phe:
0
0
50
0
0
0
9
0
9
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
0
17
0
0
25
0
9
9
0
0
9
% G
% His:
0
9
0
9
0
0
0
0
0
0
9
0
9
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
9
0
9
0
17
0
0
% I
% Lys:
0
0
9
0
0
9
0
9
9
9
9
0
0
9
50
% K
% Leu:
0
0
9
9
0
9
0
0
0
9
0
25
9
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
17
0
9
0
0
0
9
0
0
0
0
9
0
0
0
% N
% Pro:
50
0
0
0
67
0
0
0
0
9
50
9
42
9
9
% P
% Gln:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
42
0
0
0
0
9
0
0
9
0
% R
% Ser:
0
9
0
0
25
0
9
0
34
9
0
0
0
17
9
% S
% Thr:
17
25
9
9
0
0
9
9
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
42
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _