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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-5
All Species:
21.52
Human Site:
T10
Identified Species:
43.03
UniProt:
P52952
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52952
NP_004378.1
324
34918
T10
P
S
P
A
L
T
P
T
P
F
S
V
K
D
I
Chimpanzee
Pan troglodytes
XP_518104
325
35024
T10
P
S
P
A
L
T
P
T
P
F
S
V
K
D
I
Rhesus Macaque
Macaca mulatta
XP_001096796
324
34944
T10
P
S
P
A
L
T
P
T
P
F
S
V
K
D
I
Dog
Lupus familis
XP_543239
342
36276
F18
F
C
A
S
V
C
S
F
Q
M
S
D
V
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
P42582
318
34144
T10
P
S
P
A
L
T
P
T
P
F
S
V
K
D
I
Rat
Rattus norvegicus
O35767
318
34318
T10
P
S
P
A
L
T
H
T
P
F
S
V
K
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
P10
P
S
P
V
T
T
T
P
F
S
V
K
D
I
L
Frog
Xenopus laevis
P42583
299
34079
P10
A
S
P
V
T
S
T
P
F
S
V
K
D
I
L
Zebra Danio
Brachydanio rerio
Q90481
269
30288
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015473
468
50968
S76
T
S
T
Q
N
T
V
S
T
A
A
A
A
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
D12
E
T
P
S
P
V
L
D
V
K
K
E
K
N
E
Sea Urchin
Strong. purpuratus
XP_783123
344
37966
S24
P
G
N
P
S
S
F
S
V
K
S
I
L
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.8
40
N.A.
87.6
85.8
N.A.
N.A.
66.6
62.3
32.4
N.A.
26.9
N.A.
29.3
35.1
Protein Similarity:
100
99.3
97.8
49.7
N.A.
91.3
89.5
N.A.
N.A.
76.8
73.7
43.8
N.A.
40.5
N.A.
42.2
49.7
P-Site Identity:
100
100
100
6.6
N.A.
100
93.3
N.A.
N.A.
26.6
13.3
0
N.A.
13.3
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
20
N.A.
100
93.3
N.A.
N.A.
33.3
26.6
0
N.A.
33.3
N.A.
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
42
0
0
0
0
0
9
9
9
9
9
0
% A
% Cys:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
9
17
42
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% E
% Phe:
9
0
0
0
0
0
9
9
17
42
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
17
42
% I
% Lys:
0
0
0
0
0
0
0
0
0
17
9
17
50
0
0
% K
% Leu:
0
0
0
0
42
0
9
0
0
0
0
0
9
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
0
0
0
0
0
17
0
% N
% Pro:
59
0
67
9
9
0
34
17
42
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
9
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
67
0
17
9
17
9
17
0
17
59
0
0
0
9
% S
% Thr:
9
9
9
0
17
59
17
42
9
0
0
0
0
0
0
% T
% Val:
0
0
0
17
9
9
9
0
17
0
17
42
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _