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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPZA1 All Species: 56.36
Human Site: S251 Identified Species: 77.5
UniProt: P52907 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52907 NP_006126.1 286 32923 S251 S E N Y Q T M S D T T F K A L
Chimpanzee Pan troglodytes XP_513632 286 32891 S251 S E N Y Q T M S D T T F K A L
Rhesus Macaque Macaca mulatta XP_001107677 286 32932 S251 S E N Y Q T M S D T T F K A L
Dog Lupus familis XP_533066 286 32966 S251 S E N Y Q T M S D T T F K A L
Cat Felis silvestris
Mouse Mus musculus P47753 286 32921 S251 S E N Y Q T M S D T T F K A L
Rat Rattus norvegicus B2GUZ5 286 32891 S251 S E N Y Q T M S D T T F K A L
Wallaby Macropus eugenll A4D7S9 286 32928 S251 S E N Y Q T M S D T T F K A L
Platypus Ornith. anatinus Q07E00 286 32980 S251 N E N Y Q T M S D T T F K A L
Chicken Gallus gallus P13127 286 32941 S251 S E N Y Q T M S D T T F K A L
Frog Xenopus laevis P25229 256 29408 T223 N Y Q T M S D T T F K A L R R
Zebra Danio Brachydanio rerio XP_689117 286 32709 S251 S E N Y Q T M S D T T F K A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2N0 286 32741 T249 A I S E N Y Q T M S D T T F K
Honey Bee Apis mellifera XP_624862 288 32841 S253 S E N Y Q T M S D T T F K A L
Nematode Worm Caenorhab. elegans P34685 282 32163 S249 Q E N Y A N M S D T T F K A L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82631 308 35020 Y256 I R H H E T E Y L A S L E V A
Baker's Yeast Sacchar. cerevisiae P28495 268 30681 N231 D L S F F D L N E K Q F K A L
Red Bread Mold Neurospora crassa Q9P5K9 269 29610 S230 N K S F T S L S E G A F K G L
Conservation
Percent
Protein Identity: 100 96.8 99.6 97.1 N.A. 96.5 97.1 86 84.9 92.3 78.6 81.4 N.A. 63.2 64.2 55.5 N.A.
Protein Similarity: 100 97.1 99.6 98.9 N.A. 98.9 99.3 94 94 96.1 85.3 90.9 N.A. 76.2 77.7 69.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 100 93.3 100 0 100 N.A. 0 100 80 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 100 100 100 20 100 N.A. 26.6 100 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.9 32.1 35.6
Protein Similarity: N.A. N.A. N.A. 50 52.4 58
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 26.6
P-Site Similarity: N.A. N.A. N.A. 40 60 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 6 0 0 0 0 6 6 6 0 77 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 0 0 6 6 0 71 0 6 0 0 0 0 % D
% Glu: 0 71 0 6 6 0 6 0 12 0 0 0 6 0 0 % E
% Phe: 0 0 0 12 6 0 0 0 0 6 0 83 0 6 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 6 0 0 0 6 0 % G
% His: 0 0 6 6 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 6 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 6 0 0 0 0 0 0 0 6 6 0 83 0 6 % K
% Leu: 0 6 0 0 0 0 12 0 6 0 0 6 6 0 83 % L
% Met: 0 0 0 0 6 0 71 0 6 0 0 0 0 0 0 % M
% Asn: 18 0 71 0 6 6 0 6 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 6 0 6 0 65 0 6 0 0 0 6 0 0 0 0 % Q
% Arg: 0 6 0 0 0 0 0 0 0 0 0 0 0 6 6 % R
% Ser: 59 0 18 0 0 12 0 77 0 6 6 0 0 0 0 % S
% Thr: 0 0 0 6 6 71 0 12 6 71 71 6 6 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 0 71 0 6 0 6 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _