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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
22.42
Human Site:
S1094
Identified Species:
35.24
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
S1094
P
F
L
E
L
K
G
S
R
H
P
C
I
T
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
S1094
P
F
L
E
L
K
G
S
R
H
P
C
I
T
K
Dog
Lupus familis
XP_531814
1283
145094
A1050
E
E
E
E
N
G
K
A
Y
C
V
L
V
T
G
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
S1092
P
F
L
E
F
K
G
S
R
H
P
C
I
T
K
Rat
Rattus norvegicus
XP_002726765
1361
151628
S1095
P
F
L
E
L
K
G
S
R
H
P
C
I
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
A1201
P
F
L
E
L
K
N
A
R
H
P
C
I
T
K
Frog
Xenopus laevis
NP_001089247
1340
149481
S1074
P
F
L
E
L
K
G
S
R
H
P
C
I
T
K
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
S1098
P
F
L
D
L
R
G
S
R
H
P
C
V
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
M961
S
L
L
T
G
P
N
M
G
G
K
S
T
L
M
Honey Bee
Apis mellifera
XP_392346
1120
127429
A891
I
P
N
D
T
L
L
A
T
E
N
F
A
S
F
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
V957
M
G
A
S
E
A
A
V
M
L
L
T
G
P
N
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
G1067
P
Y
I
A
I
V
E
G
R
H
P
C
I
A
H
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
V1053
K
S
T
L
L
R
Q
V
C
L
A
V
I
L
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
L1053
T
G
L
G
H
P
V
L
R
G
D
S
L
G
R
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
A1013
C
Y
V
P
C
E
S
A
V
L
T
P
I
D
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
13.3
N.A.
93.3
100
N.A.
N.A.
86.6
100
80
N.A.
6.6
0
0
40
P-Site Similarity:
100
N.A.
100
26.6
N.A.
93.3
100
N.A.
N.A.
93.3
100
100
N.A.
6.6
20
0
60
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
7
7
27
0
0
7
0
7
7
7
% A
% Cys:
7
0
0
0
7
0
0
0
7
7
0
54
0
0
0
% C
% Asp:
0
0
0
14
0
0
0
0
0
0
7
0
0
7
0
% D
% Glu:
7
7
7
47
7
7
7
0
0
7
0
0
0
0
0
% E
% Phe:
0
47
0
0
7
0
0
0
0
0
0
7
0
0
7
% F
% Gly:
0
14
0
7
7
7
40
7
7
14
0
0
7
7
7
% G
% His:
0
0
0
0
7
0
0
0
0
54
0
0
0
0
7
% H
% Ile:
7
0
7
0
7
0
0
0
0
0
0
0
60
0
0
% I
% Lys:
7
0
0
0
0
40
7
0
0
0
7
0
0
0
47
% K
% Leu:
0
7
60
7
47
7
7
7
0
20
7
7
7
14
0
% L
% Met:
7
0
0
0
0
0
0
7
7
0
0
0
0
0
7
% M
% Asn:
0
0
7
0
7
0
14
0
0
0
7
0
0
0
7
% N
% Pro:
54
7
0
7
0
14
0
0
0
0
54
7
0
7
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
14
0
0
60
0
0
0
0
0
14
% R
% Ser:
7
7
0
7
0
0
7
40
0
0
0
14
0
7
0
% S
% Thr:
7
0
7
7
7
0
0
0
7
0
7
7
7
54
0
% T
% Val:
0
0
7
0
0
7
7
14
7
0
7
7
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _