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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGFG1
All Species:
13.94
Human Site:
T270
Identified Species:
25.56
UniProt:
P52594
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52594
NP_001128660.1
562
58260
T270
H
S
P
F
Q
P
Q
T
T
G
G
S
A
A
S
Chimpanzee
Pan troglodytes
XP_001137107
562
58200
T270
H
S
P
F
Q
P
Q
T
T
G
G
S
A
A
S
Rhesus Macaque
Macaca mulatta
XP_001111247
517
53144
S227
F
P
L
Q
A
T
H
S
G
S
A
A
S
V
N
Dog
Lupus familis
XP_534592
509
52244
N218
A
N
F
A
H
F
D
N
F
P
K
S
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2K6
561
58024
T270
H
S
S
F
Q
P
Q
T
T
G
G
S
A
G
S
Rat
Rattus norvegicus
Q4KLH5
561
58151
T270
H
S
P
F
Q
P
Q
T
T
G
G
S
A
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505722
521
54086
N230
H
S
P
F
Q
P
Q
N
T
G
G
S
G
A
A
Chicken
Gallus gallus
Q5F413
428
46296
D138
N
T
F
R
K
E
K
D
D
K
W
K
K
S
N
Frog
Xenopus laevis
NP_001084973
551
57755
N255
F
G
Q
S
S
G
V
N
N
F
G
A
F
P
P
Zebra Danio
Brachydanio rerio
NP_956129
556
58445
P261
A
P
T
T
A
A
F
P
S
A
P
Q
A
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624297
408
45490
A118
K
M
K
D
L
M
S
A
K
Y
E
L
K
R
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781727
429
44040
A139
A
V
L
A
A
A
K
A
K
E
A
S
E
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXE7
649
71326
Q266
E
N
L
F
P
G
R
Q
H
Q
R
T
T
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
87.5
85.2
N.A.
96.8
96.2
N.A.
82
23.3
70.1
64.9
N.A.
N.A.
30.9
N.A.
31.3
Protein Similarity:
100
99.8
87.5
85.4
N.A.
97.3
97.5
N.A.
85.5
37.9
77.2
74.7
N.A.
N.A.
45
N.A.
43.9
P-Site Identity:
100
100
0
6.6
N.A.
86.6
93.3
N.A.
80
0
6.6
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
26.6
33.3
N.A.
86.6
93.3
N.A.
86.6
40
13.3
13.3
N.A.
N.A.
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
16
24
16
0
16
0
8
16
16
39
24
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
8
8
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
8
0
0
0
8
8
0
8
0
0
% E
% Phe:
16
0
16
47
0
8
8
0
8
8
0
0
8
0
8
% F
% Gly:
0
8
0
0
0
16
0
0
8
39
47
0
8
16
0
% G
% His:
39
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
8
0
16
0
16
8
8
8
16
0
0
% K
% Leu:
0
0
24
0
8
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
16
0
0
0
0
0
24
8
0
0
0
0
0
16
% N
% Pro:
0
16
31
0
8
39
0
8
0
8
8
0
0
16
8
% P
% Gln:
0
0
8
8
39
0
39
8
0
8
0
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
8
0
0
0
8
0
0
8
0
% R
% Ser:
0
39
8
8
8
0
8
8
8
8
0
54
16
31
39
% S
% Thr:
0
8
8
8
0
8
0
31
39
0
0
8
8
0
0
% T
% Val:
0
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _