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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGFG1
All Species:
16.36
Human Site:
S146
Identified Species:
30
UniProt:
P52594
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52594
NP_001128660.1
562
58260
S146
V
H
A
S
I
S
G
S
S
A
S
S
T
S
S
Chimpanzee
Pan troglodytes
XP_001137107
562
58200
S146
V
H
A
S
I
S
G
S
S
A
S
S
T
S
S
Rhesus Macaque
Macaca mulatta
XP_001111247
517
53144
H103
G
D
S
A
P
T
L
H
L
N
K
G
T
P
S
Dog
Lupus familis
XP_534592
509
52244
L94
E
V
K
P
L
K
S
L
L
G
D
S
A
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2K6
561
58024
S146
V
H
A
S
I
S
G
S
S
A
S
S
T
S
S
Rat
Rattus norvegicus
Q4KLH5
561
58151
S146
V
H
A
S
I
S
G
S
S
A
S
S
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505722
521
54086
S106
H
A
S
I
S
G
S
S
A
S
S
T
S
S
T
Chicken
Gallus gallus
Q5F413
428
46296
A14
R
D
V
E
R
Y
Q
A
V
L
G
S
L
L
S
Frog
Xenopus laevis
NP_001084973
551
57755
E131
K
R
W
Y
V
P
P
E
Q
A
K
V
V
A
S
Zebra Danio
Brachydanio rerio
NP_956129
556
58445
A137
P
E
Q
A
K
T
V
A
S
V
H
A
S
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624297
408
45490
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781727
429
44040
L15
D
D
K
H
L
K
Q
L
R
E
M
V
S
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXE7
649
71326
E142
S
Q
D
H
V
S
S
E
D
M
T
R
R
A
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
87.5
85.2
N.A.
96.8
96.2
N.A.
82
23.3
70.1
64.9
N.A.
N.A.
30.9
N.A.
31.3
Protein Similarity:
100
99.8
87.5
85.4
N.A.
97.3
97.5
N.A.
85.5
37.9
77.2
74.7
N.A.
N.A.
45
N.A.
43.9
P-Site Identity:
100
100
13.3
6.6
N.A.
100
100
N.A.
20
13.3
13.3
13.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
33.3
20
N.A.
100
100
N.A.
60
20
26.6
46.6
N.A.
N.A.
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
31
16
0
0
0
16
8
39
0
8
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
24
8
0
0
0
0
0
8
0
8
0
0
0
0
% D
% Glu:
8
8
0
8
0
0
0
16
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
31
0
0
8
8
8
0
0
0
% G
% His:
8
31
0
16
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
31
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
16
0
8
16
0
0
0
0
16
0
0
0
0
% K
% Leu:
0
0
0
0
16
0
8
16
16
8
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
8
0
0
8
8
8
8
0
0
0
0
0
0
16
0
% P
% Gln:
0
8
8
0
0
0
16
0
8
0
0
0
0
0
0
% Q
% Arg:
8
8
0
0
8
0
0
0
8
0
0
8
8
8
0
% R
% Ser:
8
0
16
31
8
39
24
39
39
8
39
47
24
39
62
% S
% Thr:
0
0
0
0
0
16
0
0
0
0
8
8
39
0
8
% T
% Val:
31
8
8
0
16
0
8
0
8
8
0
16
8
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _