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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNA1
All Species:
27.27
Human Site:
T391
Identified Species:
46.15
UniProt:
P52294
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52294
NP_002255.3
538
60249
T391
A
L
I
S
I
L
Q
T
A
E
F
R
T
R
K
Chimpanzee
Pan troglodytes
XP_516692
546
61223
T391
A
L
I
S
I
L
Q
T
A
E
F
R
T
R
K
Rhesus Macaque
Macaca mulatta
XP_001112502
546
61137
T391
A
L
I
S
I
L
Q
T
A
E
F
R
T
R
K
Dog
Lupus familis
XP_857562
494
55356
T347
A
L
I
S
I
L
Q
T
A
E
F
R
T
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60960
538
60164
T391
A
L
I
S
I
L
Q
T
A
E
F
R
T
R
K
Rat
Rattus norvegicus
P83953
538
60118
T391
A
L
I
S
I
L
Q
T
A
E
F
R
T
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518163
554
62067
K407
V
L
I
E
I
L
Q
K
A
E
F
R
T
R
K
Chicken
Gallus gallus
Q5ZML1
538
60176
T391
A
L
I
N
I
L
Q
T
A
E
F
R
T
R
K
Frog
Xenopus laevis
P52170
522
57670
K381
P
L
V
D
L
L
N
K
G
D
F
K
A
Q
K
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
K389
V
L
I
E
I
L
Q
K
A
E
F
R
T
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52295
522
57803
K377
Q
L
R
T
V
L
E
K
G
D
F
K
A
Q
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19969
514
56144
R372
M
I
I
H
L
L
D
R
G
D
F
P
T
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96321
532
58626
N380
P
L
V
S
L
L
Q
N
A
E
F
D
I
K
K
Baker's Yeast
Sacchar. cerevisiae
Q02821
542
60423
V394
P
L
V
K
L
L
E
V
A
E
Y
K
T
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
91.2
N.A.
97.7
98.1
N.A.
78.3
95.7
44
80.3
N.A.
44.6
N.A.
42.7
N.A.
Protein Similarity:
100
98.5
98.5
91.6
N.A.
99.4
99.4
N.A.
86.8
98.3
62.2
89
N.A.
61.7
N.A.
61.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
93.3
26.6
80
N.A.
26.6
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
100
60
80
N.A.
66.6
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.2
48.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.1
66.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
0
0
0
79
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
22
0
8
0
0
0
% D
% Glu:
0
0
0
15
0
0
15
0
0
79
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
93
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
22
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
72
0
65
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
0
0
29
0
0
0
22
0
15
100
% K
% Leu:
0
93
0
0
29
100
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
22
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
72
0
0
0
0
0
0
22
0
% Q
% Arg:
0
0
8
0
0
0
0
8
0
0
0
65
0
65
0
% R
% Ser:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
50
0
0
0
0
79
0
0
% T
% Val:
15
0
22
0
8
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _