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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNA1
All Species:
25.76
Human Site:
S221
Identified Species:
43.59
UniProt:
P52294
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52294
NP_002255.3
538
60249
S221
P
P
L
L
Q
L
F
S
K
Q
N
R
L
T
M
Chimpanzee
Pan troglodytes
XP_516692
546
61223
S221
P
P
L
L
Q
L
F
S
K
Q
N
R
L
T
M
Rhesus Macaque
Macaca mulatta
XP_001112502
546
61137
S221
P
P
L
L
Q
L
F
S
K
Q
N
R
L
T
M
Dog
Lupus familis
XP_857562
494
55356
W190
T
M
T
R
N
A
V
W
A
L
S
N
L
C
R
Cat
Felis silvestris
Mouse
Mus musculus
Q60960
538
60164
S221
P
P
L
L
Q
L
F
S
K
Q
N
R
L
T
M
Rat
Rattus norvegicus
P83953
538
60118
S221
P
P
L
L
Q
L
F
S
K
Q
N
R
L
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518163
554
62067
T237
P
P
L
L
E
L
L
T
N
S
N
R
L
T
T
Chicken
Gallus gallus
Q5ZML1
538
60176
S221
P
P
L
L
Q
L
L
S
K
Q
N
R
I
T
M
Frog
Xenopus laevis
P52170
522
57670
N211
P
P
L
L
A
L
V
N
P
Q
T
P
L
G
Y
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
A219
P
S
L
Q
Q
L
L
A
K
S
N
R
L
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52295
522
57803
N207
D
G
I
L
P
L
I
N
N
E
T
P
L
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19969
514
56144
N202
Q
P
L
L
Q
F
I
N
P
E
I
P
I
G
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96321
532
58626
N210
L
P
L
L
N
Q
L
N
E
H
A
K
L
S
M
Baker's Yeast
Sacchar. cerevisiae
Q02821
542
60423
F224
M
E
P
I
L
G
L
F
N
S
N
K
P
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
91.2
N.A.
97.7
98.1
N.A.
78.3
95.7
44
80.3
N.A.
44.6
N.A.
42.7
N.A.
Protein Similarity:
100
98.5
98.5
91.6
N.A.
99.4
99.4
N.A.
86.8
98.3
62.2
89
N.A.
61.7
N.A.
61.1
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
60
86.6
46.6
60
N.A.
20
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
73.3
93.3
53.3
66.6
N.A.
46.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.2
48.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.1
66.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
8
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
0
0
0
8
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
36
8
0
0
0
0
0
0
15
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
0
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
15
0
0
0
8
0
15
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
50
0
0
15
0
0
0
% K
% Leu:
8
0
79
79
8
72
36
0
0
8
0
0
79
0
8
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
50
% M
% Asn:
0
0
0
0
15
0
0
29
22
0
65
8
0
0
0
% N
% Pro:
65
72
8
0
8
0
0
0
15
0
0
22
8
0
0
% P
% Gln:
8
0
0
8
58
8
0
0
0
50
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
58
0
0
8
% R
% Ser:
0
8
0
0
0
0
0
43
0
22
8
0
0
22
0
% S
% Thr:
8
0
8
0
0
0
0
8
0
0
15
0
0
58
15
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _