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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNH All Species: 30.3
Human Site: S304 Identified Species: 41.67
UniProt: P51946 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51946 NP_001230.1 323 37643 S304 Y E D D D Y V S K K S K H E E
Chimpanzee Pan troglodytes XP_001145999 325 37922 S304 Y E D D D Y V S K K S K H E E
Rhesus Macaque Macaca mulatta XP_001084672 323 37671 S304 Y E D D D Y V S K K S K H E E
Dog Lupus familis XP_536300 402 46441 S383 Y E D D D Y V S K K P K H E E
Cat Felis silvestris
Mouse Mus musculus Q61458 323 37488 S304 Y E D D D Y V S K K P K Q E E
Rat Rattus norvegicus Q9R1A0 323 37591 S304 Y E D D D Y V S K K P K Q E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510964 371 42563 S352 Y E D D E Y V S K K P K L E E
Chicken Gallus gallus P55168 283 33240 N265 P K P K P P P N S E G E Q G P
Frog Xenopus laevis P51947 323 37582 S304 Y E D D G Y I S K K P K T E E
Zebra Danio Brachydanio rerio NP_001013471 319 37026 V301 Y E D D D H I V K R Q M V A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524207 324 37758 A303 T D E D D M P A E D A S F H I
Honey Bee Apis mellifera XP_393939 355 41233 D325 L D E E D L Q D N E K Y A K I
Nematode Worm Caenorhab. elegans Q9TYP2 302 34995 M278 K E E V K K L M A K L P K P N
Sea Urchin Strong. purpuratus XP_787341 266 30836 V248 P K D L P D I V N T I K R E H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W5S1 336 38112 S309 H S S S H D E S K K R E K R S
Baker's Yeast Sacchar. cerevisiae P37366 393 45192 A359 E E A K K I A A K N Y Y C Q N
Red Bread Mold Neurospora crassa Q9HE63 345 38453 E314 A M V D C T Q E L I S F Y E C
Conservation
Percent
Protein Identity: 100 96 99.3 78.1 N.A. 95 95.3 N.A. 73.3 24.7 71.2 65.6 N.A. 44.4 42.5 20.1 42.4
Protein Similarity: 100 96.6 100 79.5 N.A. 99 99.3 N.A. 81.1 43 84.8 83.2 N.A. 64.8 59.7 38.7 58.8
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 80 0 73.3 40 N.A. 13.3 6.6 13.3 20
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 86.6 26.6 80 66.6 N.A. 46.6 40 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. 30.6 23.6 23.4
Protein Similarity: N.A. N.A. N.A. 53.2 41.7 43.1
P-Site Identity: N.A. N.A. N.A. 20 13.3 20
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 0 0 0 6 12 6 0 6 0 6 6 0 % A
% Cys: 0 0 0 0 6 0 0 0 0 0 0 0 6 0 6 % C
% Asp: 0 12 59 65 53 12 0 6 0 6 0 0 0 0 6 % D
% Glu: 6 65 18 6 6 0 6 6 6 12 0 12 0 59 48 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 6 6 0 0 % F
% Gly: 0 0 0 0 6 0 0 0 0 0 6 0 0 6 0 % G
% His: 6 0 0 0 6 6 0 0 0 0 0 0 24 6 6 % H
% Ile: 0 0 0 0 0 6 18 0 0 6 6 0 0 0 12 % I
% Lys: 6 12 0 12 12 6 0 0 65 59 6 53 12 6 0 % K
% Leu: 6 0 0 6 0 6 6 0 6 0 6 0 6 0 0 % L
% Met: 0 6 0 0 0 6 0 6 0 0 0 6 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 6 12 6 0 0 0 0 12 % N
% Pro: 12 0 6 0 12 6 12 0 0 0 30 6 0 6 6 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 6 0 18 6 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 6 6 0 6 6 0 % R
% Ser: 0 6 6 6 0 0 0 53 6 0 24 6 0 0 6 % S
% Thr: 6 0 0 0 0 6 0 0 0 6 0 0 6 0 0 % T
% Val: 0 0 6 6 0 0 42 12 0 0 0 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 53 0 0 0 0 48 0 0 0 0 6 12 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _