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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNH
All Species:
35.45
Human Site:
S122
Identified Species:
48.75
UniProt:
P51946
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51946
NP_001230.1
323
37643
S122
V
D
E
F
N
V
S
S
P
Q
F
V
G
N
L
Chimpanzee
Pan troglodytes
XP_001145999
325
37922
S122
V
D
E
F
N
V
S
S
P
Q
F
V
G
N
L
Rhesus Macaque
Macaca mulatta
XP_001084672
323
37671
S122
V
D
E
F
N
V
S
S
P
Q
F
V
G
N
L
Dog
Lupus familis
XP_536300
402
46441
S201
V
D
E
F
N
V
S
S
P
Q
F
V
G
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61458
323
37488
S122
V
D
E
F
N
V
S
S
P
Q
F
V
G
N
L
Rat
Rattus norvegicus
Q9R1A0
323
37591
S122
V
D
E
F
N
V
S
S
P
Q
F
V
G
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510964
371
42563
S170
V
D
E
F
N
V
S
S
I
Q
F
V
G
N
V
Chicken
Gallus gallus
P55168
283
33240
M86
K
S
I
D
P
V
L
M
A
P
T
C
V
F
L
Frog
Xenopus laevis
P51947
323
37582
S122
V
D
E
F
N
V
S
S
I
Q
F
V
G
N
L
Zebra Danio
Brachydanio rerio
NP_001013471
319
37026
S122
V
D
E
F
N
V
S
S
T
Q
F
V
G
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524207
324
37758
I122
V
E
E
F
N
V
S
I
N
Q
F
V
N
N
I
Honey Bee
Apis mellifera
XP_393939
355
41233
I146
V
E
E
F
N
V
S
I
Y
Q
F
V
A
N
I
Nematode Worm
Caenorhab. elegans
Q9TYP2
302
34995
A99
P
F
L
V
A
S
T
A
L
F
L
A
C
K
V
Sea Urchin
Strong. purpuratus
XP_787341
266
30836
K69
F
L
L
R
A
F
C
K
K
F
Q
P
P
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W5S1
336
38112
C129
P
K
E
I
M
L
T
C
V
Y
A
A
C
K
I
Baker's Yeast
Sacchar. cerevisiae
P37366
393
45192
V180
S
E
N
Y
F
I
S
V
D
S
F
A
Q
K
A
Red Bread Mold
Neurospora crassa
Q9HE63
345
38453
I111
M
E
E
C
P
Q
H
I
R
L
M
A
N
E
A
Conservation
Percent
Protein Identity:
100
96
99.3
78.1
N.A.
95
95.3
N.A.
73.3
24.7
71.2
65.6
N.A.
44.4
42.5
20.1
42.4
Protein Similarity:
100
96.6
100
79.5
N.A.
99
99.3
N.A.
81.1
43
84.8
83.2
N.A.
64.8
59.7
38.7
58.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
13.3
93.3
93.3
N.A.
66.6
66.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
13.3
93.3
93.3
N.A.
80
80
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
23.6
23.4
Protein Similarity:
N.A.
N.A.
N.A.
53.2
41.7
43.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
6
6
0
6
24
6
0
12
% A
% Cys:
0
0
0
6
0
0
6
6
0
0
0
6
12
0
0
% C
% Asp:
0
53
0
6
0
0
0
0
6
0
0
0
0
0
0
% D
% Glu:
0
24
77
0
0
0
0
0
0
0
0
0
0
6
0
% E
% Phe:
6
6
0
65
6
6
0
0
0
12
71
0
0
6
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
53
0
0
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
6
0
6
0
18
12
0
0
0
0
0
18
% I
% Lys:
6
6
0
0
0
0
0
6
6
0
0
0
0
18
0
% K
% Leu:
0
6
12
0
0
6
6
0
6
6
6
0
0
0
53
% L
% Met:
6
0
0
0
6
0
0
6
0
0
6
0
0
0
0
% M
% Asn:
0
0
6
0
65
0
0
0
6
0
0
0
12
65
0
% N
% Pro:
12
0
0
0
12
0
0
0
36
6
0
6
6
0
6
% P
% Gln:
0
0
0
0
0
6
0
0
0
65
6
0
6
0
0
% Q
% Arg:
0
0
0
6
0
0
0
0
6
0
0
0
0
0
0
% R
% Ser:
6
6
0
0
0
6
71
53
0
6
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
0
6
0
6
0
0
0
0
% T
% Val:
65
0
0
6
0
71
0
6
6
0
0
65
6
6
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
6
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _