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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN7
All Species:
23.94
Human Site:
T121
Identified Species:
40.51
UniProt:
P51798
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51798
NP_001107803.1
805
88679
T121
I
N
H
T
A
F
R
T
V
E
I
K
R
W
V
Chimpanzee
Pan troglodytes
XP_001159424
805
88612
T121
I
N
H
T
A
F
R
T
V
E
I
K
R
W
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537014
809
88988
T125
I
N
H
T
A
F
R
T
V
E
M
K
R
W
V
Cat
Felis silvestris
Mouse
Mus musculus
O70496
803
88694
T119
I
N
H
T
A
F
R
T
V
E
I
K
R
W
V
Rat
Rattus norvegicus
P51799
803
88712
T119
I
N
H
T
A
F
R
T
V
E
I
K
R
W
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516953
776
85812
G105
W
V
I
C
A
M
I
G
I
L
T
G
L
V
A
Chicken
Gallus gallus
NP_001025815
802
88577
T117
I
N
H
A
A
F
R
T
V
E
I
K
R
W
V
Frog
Xenopus laevis
Q9W701
689
76782
F53
R
I
G
D
D
W
Y
F
L
F
A
L
G
V
I
Zebra Danio
Brachydanio rerio
NP_001071005
795
88330
C108
M
S
Q
M
G
F
R
C
L
E
I
T
R
W
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
K119
K
G
Y
K
F
V
V
K
K
N
F
A
R
W
F
Nematode Worm
Caenorhab. elegans
NP_506022
796
89213
L108
N
R
W
F
V
C
F
L
I
G
V
F
T
G
L
Sea Urchin
Strong. purpuratus
XP_796968
803
89073
V111
I
S
S
K
S
V
H
V
L
Q
K
E
L
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
K105
V
E
N
F
A
G
W
K
F
A
L
T
F
A
I
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
T105
E
T
L
V
N
W
K
T
G
H
C
Q
R
N
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
94.4
N.A.
96.4
96.2
N.A.
89.4
85.9
24.2
76.1
N.A.
N.A.
51.4
46.7
55.2
Protein Similarity:
100
99.8
N.A.
97.6
N.A.
97.8
97.8
N.A.
93.1
92.1
42.1
86.2
N.A.
N.A.
69.8
64.8
71.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
6.6
93.3
0
46.6
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
93.3
20
66.6
N.A.
N.A.
20
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.6
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
58
0
0
0
0
8
8
8
0
8
8
% A
% Cys:
0
0
0
8
0
8
0
8
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
0
0
0
50
0
8
0
0
0
% E
% Phe:
0
0
0
15
8
50
8
8
8
8
8
8
8
0
8
% F
% Gly:
0
8
8
0
8
8
0
8
8
8
0
8
8
8
0
% G
% His:
0
0
43
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
50
8
8
0
0
0
8
0
15
0
43
0
0
0
15
% I
% Lys:
8
0
0
15
0
0
8
15
8
0
8
43
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
8
22
8
8
8
15
0
8
% L
% Met:
8
0
0
8
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
43
8
0
8
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
8
8
0
0
0
0
50
0
0
0
0
0
65
0
8
% R
% Ser:
0
15
8
0
8
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
8
0
36
0
0
0
50
0
0
8
15
8
0
0
% T
% Val:
8
8
0
8
8
15
8
8
43
0
8
0
0
15
50
% V
% Trp:
8
0
8
0
0
15
8
0
0
0
0
0
0
58
8
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _