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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN6
All Species:
9.39
Human Site:
S405
Identified Species:
15.9
UniProt:
P51797
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51797
NP_001277.1
869
97217
S405
E
C
R
Q
M
S
S
S
S
Q
I
G
N
D
S
Chimpanzee
Pan troglodytes
XP_514393
802
89426
V354
Q
L
Q
V
T
E
D
V
N
S
S
I
K
T
F
Rhesus Macaque
Macaca mulatta
XP_001104721
869
97094
S405
E
C
R
Q
M
S
S
S
S
Q
I
G
N
D
S
Dog
Lupus familis
XP_535404
889
99260
G425
C
R
Q
M
S
A
S
G
Q
I
G
N
D
S
F
Cat
Felis silvestris
Mouse
Mus musculus
O35454
870
96962
S406
C
R
Q
M
S
S
T
S
Q
T
G
N
G
S
F
Rat
Rattus norvegicus
P51799
803
88712
L355
W
D
L
S
S
P
G
L
I
N
F
G
R
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516296
878
97865
K417
C
L
N
K
R
L
A
K
Y
R
M
R
N
V
H
Chicken
Gallus gallus
XP_417644
868
97172
S404
C
R
Q
M
S
S
T
S
H
T
G
N
D
T
W
Frog
Xenopus laevis
Q9W701
689
76782
F241
I
R
N
Y
W
R
G
F
F
A
A
T
C
G
A
Zebra Danio
Brachydanio rerio
XP_696527
863
96883
S400
G
E
C
R
D
L
V
S
N
V
N
N
N
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
G355
Y
P
G
L
L
N
L
G
K
F
E
T
I
P
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193438
761
83935
A313
K
V
A
R
V
L
E
A
V
L
V
A
L
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
M344
F
N
Q
L
T
L
Y
M
T
S
W
R
R
N
S
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
Y331
V
I
L
F
N
V
T
Y
D
R
D
W
K
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
99.4
93.3
N.A.
96.7
40.8
N.A.
81.3
93.2
22.7
82.6
N.A.
N.A.
37.9
N.A.
49.8
Protein Similarity:
100
92.2
99.8
95.1
N.A.
98.7
58
N.A.
85.3
97.8
39.1
90.7
N.A.
N.A.
57.3
N.A.
64.6
P-Site Identity:
100
0
100
6.6
N.A.
13.3
6.6
N.A.
6.6
13.3
0
20
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
20
100
26.6
N.A.
26.6
6.6
N.A.
33.3
33.3
6.6
33.3
N.A.
N.A.
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
30
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
8
8
0
8
8
8
0
0
8
% A
% Cys:
29
15
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
0
8
0
8
0
8
0
8
0
15
15
8
% D
% Glu:
15
8
0
0
0
8
8
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
8
0
0
0
8
8
8
8
0
0
8
22
% F
% Gly:
8
0
8
0
0
0
15
15
0
0
22
22
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
8
8
0
0
0
0
0
0
8
8
15
8
8
0
0
% I
% Lys:
8
0
0
8
0
0
0
8
8
0
0
0
15
0
0
% K
% Leu:
0
15
15
15
8
29
8
8
0
8
0
0
8
0
0
% L
% Met:
0
0
0
22
15
0
0
8
0
0
8
0
0
0
0
% M
% Asn:
0
8
15
0
8
8
0
0
15
8
8
29
29
8
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
36
15
0
0
0
0
15
15
0
0
0
0
8
% Q
% Arg:
0
29
15
15
8
8
0
0
0
15
0
15
15
0
0
% R
% Ser:
0
0
0
8
29
29
22
36
15
15
8
0
0
15
29
% S
% Thr:
0
0
0
0
15
0
22
0
8
15
0
15
0
22
8
% T
% Val:
8
8
0
8
8
8
8
8
8
8
8
0
0
22
0
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
8
8
0
0
8
% W
% Tyr:
8
0
0
8
0
0
8
8
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _