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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN5
All Species:
39.09
Human Site:
Y558
Identified Species:
71.67
UniProt:
P51795
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51795
NP_000075.1
746
83147
Y558
A
L
G
R
E
G
I
Y
D
A
H
I
R
L
N
Chimpanzee
Pan troglodytes
XP_001154165
791
87957
Y603
A
F
G
R
E
G
I
Y
E
A
H
I
R
L
N
Rhesus Macaque
Macaca mulatta
XP_001083068
746
83128
Y558
A
L
G
R
E
G
I
Y
D
A
H
I
R
L
N
Dog
Lupus familis
XP_549002
992
108374
Y804
A
L
G
R
E
G
I
Y
D
A
H
I
R
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVD4
746
83082
Y558
A
L
G
R
E
G
I
Y
D
A
H
I
R
L
N
Rat
Rattus norvegicus
P51796
746
83049
Y558
A
L
G
R
E
G
I
Y
D
A
H
I
R
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515028
869
97095
Y681
A
F
G
K
E
G
I
Y
E
A
H
I
H
L
N
Chicken
Gallus gallus
XP_420265
942
104254
Y754
A
I
G
R
E
G
I
Y
D
A
H
I
R
L
N
Frog
Xenopus laevis
NP_001080969
808
90050
Y620
A
L
G
R
G
S
I
Y
D
A
H
I
H
L
N
Zebra Danio
Brachydanio rerio
XP_001920783
811
89757
Y623
A
L
G
R
E
G
I
Y
E
A
H
I
R
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
M701
L
V
D
S
P
D
N
M
I
L
L
G
S
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
E563
A
F
N
E
G
L
Y
E
V
Q
A
R
L
K
G
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
F567
Q
M
I
M
V
N
G
F
P
Y
L
E
D
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.6
99.7
74.2
N.A.
97.9
98.2
N.A.
66.5
71
79.2
76.6
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
83.3
100
74.9
N.A.
99.3
99.4
N.A.
76.8
75.3
85.6
84.4
N.A.
35.2
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
100
100
N.A.
73.3
93.3
80
93.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
86.6
100
80
100
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
53.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
85
0
0
0
0
0
0
0
0
77
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
54
0
0
0
8
0
0
% D
% Glu:
0
0
0
8
70
0
0
8
24
0
0
8
0
8
0
% E
% Phe:
0
24
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
77
0
16
70
8
0
0
0
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
77
0
16
0
0
% H
% Ile:
0
8
8
0
0
0
77
0
8
0
0
77
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
8
54
0
0
0
8
0
0
0
8
16
0
8
77
0
% L
% Met:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
77
% N
% Pro:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
16
% Q
% Arg:
0
0
0
70
0
0
0
0
0
0
0
8
62
0
0
% R
% Ser:
0
0
0
8
0
8
0
0
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
77
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _