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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN5
All Species:
26.67
Human Site:
Y425
Identified Species:
48.89
UniProt:
P51795
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51795
NP_000075.1
746
83147
Y425
R
P
A
G
V
G
V
Y
S
A
M
W
Q
L
A
Chimpanzee
Pan troglodytes
XP_001154165
791
87957
V469
D
R
P
A
G
I
G
V
Y
S
A
I
W
Q
L
Rhesus Macaque
Macaca mulatta
XP_001083068
746
83128
Y425
R
P
A
G
V
G
V
Y
S
A
M
W
Q
L
A
Dog
Lupus familis
XP_549002
992
108374
Y671
R
P
A
G
V
G
V
Y
S
A
M
W
Q
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVD4
746
83082
Y425
R
P
A
G
V
G
I
Y
S
A
M
W
Q
L
A
Rat
Rattus norvegicus
P51796
746
83049
Y425
R
P
A
G
V
G
V
Y
S
A
M
W
Q
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515028
869
97095
V547
D
R
P
A
G
V
G
V
Y
T
A
M
W
Q
L
Chicken
Gallus gallus
XP_420265
942
104254
Y621
R
A
A
G
P
G
V
Y
T
A
M
W
Q
L
A
Frog
Xenopus laevis
NP_001080969
808
90050
Y487
R
A
A
G
N
G
V
Y
T
A
M
W
Q
L
S
Zebra Danio
Brachydanio rerio
XP_001920783
811
89757
V489
D
R
P
A
G
P
D
V
Y
T
A
M
W
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
T508
T
H
W
M
T
S
Y
T
S
V
F
G
N
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
F426
Y
N
D
L
A
T
I
F
F
N
T
Q
D
D
A
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
L438
N
T
H
A
F
E
F
L
K
I
F
T
S
L
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.6
99.7
74.2
N.A.
97.9
98.2
N.A.
66.5
71
79.2
76.6
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
83.3
100
74.9
N.A.
99.3
99.4
N.A.
76.8
75.3
85.6
84.4
N.A.
35.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
93.3
100
N.A.
0
80
73.3
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
0
86.6
86.6
0
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
53.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
54
31
8
0
0
0
0
54
24
0
0
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
24
0
8
0
0
0
8
0
0
0
0
0
8
8
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
8
8
8
0
16
0
0
0
0
% F
% Gly:
0
0
0
54
24
54
16
0
0
0
0
8
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
16
0
0
8
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
8
0
0
0
0
0
70
24
% L
% Met:
0
0
0
8
0
0
0
0
0
0
54
16
0
0
0
% M
% Asn:
8
8
0
0
8
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
39
24
0
8
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
54
24
0
% Q
% Arg:
54
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
47
8
0
0
8
0
8
% S
% Thr:
8
8
0
0
8
8
0
8
16
16
8
8
0
0
0
% T
% Val:
0
0
0
0
39
8
47
24
0
8
0
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
54
24
0
0
% W
% Tyr:
8
0
0
0
0
0
8
54
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _