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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN5
All Species:
41.21
Human Site:
Y376
Identified Species:
75.56
UniProt:
P51795
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51795
NP_000075.1
746
83147
Y376
I
L
A
F
P
N
E
Y
T
R
M
S
T
S
E
Chimpanzee
Pan troglodytes
XP_001154165
791
87957
Y420
V
I
A
F
P
N
P
Y
T
R
L
N
T
S
E
Rhesus Macaque
Macaca mulatta
XP_001083068
746
83128
Y376
I
L
A
F
P
N
E
Y
T
R
M
S
T
S
E
Dog
Lupus familis
XP_549002
992
108374
Y622
I
L
A
F
P
N
E
Y
T
R
M
S
T
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVD4
746
83082
Y376
I
L
A
F
P
N
E
Y
T
R
M
S
T
S
E
Rat
Rattus norvegicus
P51796
746
83049
Y376
I
L
A
F
P
N
E
Y
T
R
M
S
T
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515028
869
97095
Y498
L
V
A
Y
P
N
P
Y
T
R
Q
S
T
S
E
Chicken
Gallus gallus
XP_420265
942
104254
Y572
I
L
A
F
P
N
E
Y
T
R
M
S
T
S
E
Frog
Xenopus laevis
NP_001080969
808
90050
Y438
I
L
A
F
P
N
D
Y
T
R
M
S
S
S
E
Zebra Danio
Brachydanio rerio
XP_001920783
811
89757
Y440
V
L
A
F
P
N
S
Y
T
R
M
S
T
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
S459
A
L
L
V
S
S
I
S
F
P
L
G
T
G
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
G377
I
T
S
A
I
S
F
G
L
P
L
L
R
K
C
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
L389
F
L
A
T
L
T
A
L
I
S
Y
F
N
E
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.6
99.7
74.2
N.A.
97.9
98.2
N.A.
66.5
71
79.2
76.6
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
83.3
100
74.9
N.A.
99.3
99.4
N.A.
76.8
75.3
85.6
84.4
N.A.
35.2
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
100
100
N.A.
100
100
N.A.
66.6
100
86.6
86.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
86.6
100
100
93.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
53.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
85
8
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
47
0
0
0
0
0
0
8
77
% E
% Phe:
8
0
0
70
0
0
8
0
8
0
0
8
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
62
8
0
0
8
0
8
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
8
77
8
0
8
0
0
8
8
0
24
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% M
% Asn:
0
0
0
0
0
77
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
77
0
16
0
0
16
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
77
0
0
8
0
0
% R
% Ser:
0
0
8
0
8
16
8
8
0
8
0
70
8
77
0
% S
% Thr:
0
8
0
8
0
8
0
0
77
0
0
0
77
0
0
% T
% Val:
16
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
77
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _