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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN5
All Species:
31.52
Human Site:
S666
Identified Species:
57.78
UniProt:
P51795
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51795
NP_000075.1
746
83147
S666
I
I
Y
F
T
E
H
S
P
P
L
P
P
Y
T
Chimpanzee
Pan troglodytes
XP_001154165
791
87957
T711
R
V
C
F
A
Q
H
T
P
S
L
P
A
E
S
Rhesus Macaque
Macaca mulatta
XP_001083068
746
83128
S666
I
I
Y
F
T
E
H
S
P
P
L
P
P
Y
T
Dog
Lupus familis
XP_549002
992
108374
S912
I
I
Y
F
T
E
H
S
P
P
M
P
P
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVD4
746
83082
S666
I
I
Y
F
T
E
H
S
P
P
M
P
P
Y
T
Rat
Rattus norvegicus
P51796
746
83049
S666
I
I
Y
F
T
E
H
S
P
P
M
P
P
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515028
869
97095
P789
I
M
Y
F
T
E
D
P
P
E
L
A
A
N
S
Chicken
Gallus gallus
XP_420265
942
104254
S862
I
I
Y
F
T
D
H
S
P
P
L
P
P
S
S
Frog
Xenopus laevis
NP_001080969
808
90050
T728
R
I
Y
F
T
E
H
T
P
T
Q
P
T
T
A
Zebra Danio
Brachydanio rerio
XP_001920783
811
89757
T731
R
I
F
F
T
E
Y
T
P
P
Q
P
P
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
V969
R
F
A
N
E
V
G
V
N
G
S
P
T
R
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
G681
A
K
P
V
S
S
K
G
L
C
I
E
D
I
H
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
E674
Y
F
N
K
S
N
E
E
L
G
H
R
E
N
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.6
99.7
74.2
N.A.
97.9
98.2
N.A.
66.5
71
79.2
76.6
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
83.3
100
74.9
N.A.
99.3
99.4
N.A.
76.8
75.3
85.6
84.4
N.A.
35.2
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
93.3
N.A.
93.3
93.3
N.A.
46.6
80
53.3
53.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
100
N.A.
100
100
N.A.
60
93.3
60
80
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
53.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
0
0
0
0
0
8
16
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
8
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
8
62
8
8
0
8
0
8
8
8
0
% E
% Phe:
0
16
8
77
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
0
16
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
62
0
0
0
8
0
0
0
8
% H
% Ile:
54
62
0
0
0
0
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
16
0
39
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
24
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
0
0
8
0
0
0
0
24
0
% N
% Pro:
0
0
8
0
0
0
0
8
77
54
0
77
54
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
16
0
0
0
0
% Q
% Arg:
31
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% R
% Ser:
0
0
0
0
16
8
0
47
0
8
8
0
0
8
31
% S
% Thr:
0
0
0
0
70
0
0
24
0
8
0
0
16
8
47
% T
% Val:
0
8
0
8
0
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
62
0
0
0
8
0
0
0
0
0
0
39
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _