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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN5
All Species:
30.3
Human Site:
S40
Identified Species:
55.56
UniProt:
P51795
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51795
NP_000075.1
746
83147
S40
H
R
E
I
T
N
K
S
K
E
S
T
W
A
L
Chimpanzee
Pan troglodytes
XP_001154165
791
87957
K84
H
R
R
I
N
S
K
K
K
E
S
A
W
E
M
Rhesus Macaque
Macaca mulatta
XP_001083068
746
83128
S40
H
R
E
I
T
N
K
S
K
E
S
T
W
A
L
Dog
Lupus familis
XP_549002
992
108374
S286
H
R
E
I
T
N
K
S
K
E
S
T
W
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVD4
746
83082
S40
H
R
E
I
T
N
K
S
K
E
S
T
W
A
L
Rat
Rattus norvegicus
P51796
746
83049
S40
H
R
E
I
T
N
K
S
K
E
S
T
W
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515028
869
97095
S162
H
R
K
I
T
S
K
S
K
E
S
I
W
E
F
Chicken
Gallus gallus
XP_420265
942
104254
R236
R
H
R
E
I
T
S
R
S
K
E
S
T
W
A
Frog
Xenopus laevis
NP_001080969
808
90050
S102
H
R
E
I
L
S
R
S
K
E
S
T
W
A
L
Zebra Danio
Brachydanio rerio
XP_001920783
811
89757
S104
H
R
E
I
A
I
K
S
K
E
S
T
W
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
D115
M
Y
G
R
Y
T
K
D
L
G
E
F
A
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
S36
D
D
I
T
L
L
N
S
H
R
D
G
D
G
G
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
L58
V
D
S
D
R
E
F
L
N
S
K
Y
R
H
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.6
99.7
74.2
N.A.
97.9
98.2
N.A.
66.5
71
79.2
76.6
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
83.3
100
74.9
N.A.
99.3
99.4
N.A.
76.8
75.3
85.6
84.4
N.A.
35.2
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
100
100
N.A.
66.6
0
80
86.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
80
13.3
93.3
86.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
53.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
8
8
54
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
8
0
0
0
8
0
0
8
0
8
0
8
% D
% Glu:
0
0
54
8
0
8
0
0
0
70
16
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
8
0
8
0
8
8
% G
% His:
70
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
0
8
70
8
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
0
0
70
8
70
8
8
0
0
8
0
% K
% Leu:
0
0
0
0
16
8
0
8
8
0
0
0
0
0
54
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
39
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
70
16
8
8
0
8
8
0
8
0
0
8
0
0
% R
% Ser:
0
0
8
0
0
24
8
70
8
8
70
8
0
0
0
% S
% Thr:
0
0
0
8
47
16
0
0
0
0
0
54
8
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
70
8
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _