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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH3A2
All Species:
22.42
Human Site:
S446
Identified Species:
49.33
UniProt:
P51648
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51648
NP_000373.1
485
54848
S446
R
Y
P
P
N
S
Q
S
K
V
D
W
G
K
F
Chimpanzee
Pan troglodytes
XP_001152933
485
54797
S446
R
Y
P
P
N
S
Q
S
K
V
D
W
G
K
F
Rhesus Macaque
Macaca mulatta
XP_001101124
485
54726
S446
R
Y
P
P
N
S
Q
S
K
V
D
W
G
K
F
Dog
Lupus familis
XP_536656
485
54244
S446
R
Y
P
P
N
S
Q
S
K
V
D
W
A
K
F
Cat
Felis silvestris
Mouse
Mus musculus
P47740
484
53924
S446
R
Y
P
P
N
S
E
S
K
V
S
W
A
K
F
Rat
Rattus norvegicus
P30839
484
54063
S446
R
Y
P
P
N
S
E
S
K
V
S
W
S
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508369
491
54456
K449
R
Y
P
P
S
P
L
K
V
T
P
Q
R
F
P
Chicken
Gallus gallus
NP_001006223
490
53992
K449
R
Y
P
P
S
S
Q
K
K
L
D
W
A
K
F
Frog
Xenopus laevis
NP_001085341
506
57110
K446
R
Y
P
P
Y
S
M
K
K
V
E
W
A
K
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q70DU8
484
53140
Y443
S
H
K
K
A
V
L
Y
R
S
L
F
G
D
S
Baker's Yeast
Sacchar. cerevisiae
Q04458
532
59960
Q485
R
Y
P
P
N
S
A
Q
K
E
K
L
V
R
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.2
88.2
N.A.
83.3
84.3
N.A.
64.7
71.2
64
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
98.5
94
N.A.
91.1
92.3
N.A.
79.8
83.8
79.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
26.6
73.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
33.3
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.7
30.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.8
51.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
0
0
37
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
46
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
19
0
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
82
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
0
0
0
28
82
0
10
0
0
73
0
% K
% Leu:
0
0
0
0
0
0
19
0
0
10
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
91
91
0
10
0
0
0
0
10
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
46
10
0
0
0
10
0
0
0
% Q
% Arg:
91
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% R
% Ser:
10
0
0
0
19
82
0
55
0
10
19
0
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
10
64
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% W
% Tyr:
0
91
0
0
10
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _