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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDH3G
All Species:
30
Human Site:
S175
Identified Species:
60
UniProt:
P51553
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51553
NP_004126.1
393
42794
S175
E
N
T
E
G
E
Y
S
S
L
E
H
E
S
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70404
393
42767
S175
E
N
T
E
G
E
Y
S
S
L
E
H
E
S
V
Rat
Rattus norvegicus
P41565
393
42833
S175
E
N
T
E
G
E
Y
S
S
L
E
H
E
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511168
376
41276
S158
E
N
T
E
G
E
Y
S
S
L
E
H
E
S
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086122
391
42851
S173
E
N
T
E
G
E
Y
S
S
L
E
H
E
S
V
Zebra Danio
Brachydanio rerio
XP_699839
289
31870
L103
I
A
D
Y
A
F
K
L
A
R
E
K
G
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWH4
377
40826
S170
E
N
T
E
G
E
Y
S
G
I
E
H
E
I
V
Honey Bee
Apis mellifera
XP_393876
384
42391
A172
Q
N
T
E
G
E
Y
A
M
L
E
H
E
S
V
Nematode Worm
Caenorhab. elegans
Q93353
379
41534
S169
E
Q
T
E
G
E
Y
S
S
L
E
H
E
L
V
Sea Urchin
Strong. purpuratus
XP_001175786
362
39467
V157
H
E
N
V
D
G
V
V
E
S
L
K
I
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q945K7
374
40606
S166
E
N
T
E
G
E
Y
S
G
L
E
H
Q
V
V
Baker's Yeast
Sacchar. cerevisiae
P28834
360
39306
V155
S
G
L
E
H
E
S
V
P
G
V
V
E
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
95.1
95.6
N.A.
88.8
N.A.
77.8
56.7
N.A.
40.9
53.6
47.5
60
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
97.1
97.9
N.A.
92.3
N.A.
85.7
64.6
N.A.
60.3
68.9
65.3
73.7
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
100
N.A.
100
6.6
N.A.
80
80
86.6
0
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
100
N.A.
100
13.3
N.A.
86.6
93.3
86.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
44
45.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
9
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
67
9
0
84
0
84
0
0
9
0
84
0
75
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
75
9
0
0
17
9
0
0
9
0
0
% G
% His:
9
0
0
0
9
0
0
0
0
0
0
75
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
0
0
9
17
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
17
0
0
0
% K
% Leu:
0
0
9
0
0
0
0
9
0
67
9
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
67
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
9
% R
% Ser:
9
0
0
0
0
0
9
67
50
9
0
0
0
59
0
% S
% Thr:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
0
0
9
0
0
9
17
0
0
9
9
0
9
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
75
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _