KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB27A
All Species:
40.91
Human Site:
Y159
Identified Species:
60
UniProt:
P51159
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51159
NP_004571.2
221
24868
Y159
A
E
K
Y
G
I
P
Y
F
E
T
S
A
A
N
Chimpanzee
Pan troglodytes
XP_510426
221
24917
Y159
A
E
K
Y
G
I
P
Y
F
E
T
S
A
A
N
Rhesus Macaque
Macaca mulatta
XP_001089307
221
24877
Y159
A
E
K
Y
G
I
P
Y
F
E
T
S
A
A
N
Dog
Lupus familis
XP_541092
256
28618
Y197
A
D
K
Y
G
I
P
Y
F
E
T
S
A
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERI2
221
24999
Y159
A
E
K
Y
G
I
P
Y
F
E
T
S
A
A
N
Rat
Rattus norvegicus
P23640
221
25050
Y159
A
E
K
Y
G
I
P
Y
F
E
T
S
A
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509953
315
35118
Y256
A
D
K
Y
G
L
P
Y
F
E
T
S
A
A
T
Chicken
Gallus gallus
Q5F470
207
23503
A154
F
M
E
T
S
A
K
A
N
I
N
I
E
N
A
Frog
Xenopus laevis
NP_001087958
221
25021
Y159
A
E
K
Y
G
I
P
Y
F
E
T
S
A
A
N
Zebra Danio
Brachydanio rerio
NP_001025428
222
25064
Y159
A
E
K
Y
G
V
P
Y
F
E
T
S
A
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25228
220
24843
F160
A
D
Q
L
G
V
E
F
F
E
T
S
A
K
E
Honey Bee
Apis mellifera
XP_394733
208
24017
S155
G
L
V
Y
L
E
T
S
A
A
T
G
Q
N
V
Nematode Worm
Caenorhab. elegans
Q94986
219
24741
F161
A
D
Q
L
G
L
E
F
F
E
T
S
A
K
E
Sea Urchin
Strong. purpuratus
XP_001190480
289
32303
Y225
A
E
K
Y
G
L
P
Y
F
E
T
S
A
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28186
216
23816
T162
F
F
E
T
S
A
K
T
N
L
N
V
E
E
V
Baker's Yeast
Sacchar. cerevisiae
P07560
215
23487
F158
A
K
E
L
G
I
P
F
I
E
S
S
A
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.7
61.3
N.A.
95.9
96.3
N.A.
49.5
40.7
88.6
83.3
N.A.
42.9
64.7
41.1
56.4
Protein Similarity:
100
99.5
98.6
71.8
N.A.
96.3
96.8
N.A.
58.7
61
96.3
90
N.A.
64.7
79.1
65.1
64
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
80
0
100
93.3
N.A.
46.6
13.3
46.6
80
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
6.6
100
100
N.A.
73.3
13.3
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.5
40.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.8
64.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
82
0
0
0
0
13
0
7
7
7
0
0
82
57
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
50
19
0
0
7
13
0
0
82
0
0
13
7
13
% E
% Phe:
13
7
0
0
0
0
0
19
75
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
82
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
50
0
0
7
7
0
7
0
0
0
% I
% Lys:
0
7
63
0
0
0
13
0
0
0
0
0
0
25
0
% K
% Leu:
0
7
0
19
7
19
0
0
0
7
0
0
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
13
0
0
13
50
% N
% Pro:
0
0
0
0
0
0
69
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
13
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
13
0
0
7
0
0
7
82
0
0
7
% S
% Thr:
0
0
0
13
0
0
7
7
0
0
82
0
0
0
13
% T
% Val:
0
0
7
0
0
13
0
0
0
0
0
7
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
69
0
0
0
63
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _