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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB27A
All Species:
4.55
Human Site:
S56
Identified Species:
6.67
UniProt:
P51159
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51159
NP_004571.2
221
24868
S56
K
R
V
V
Y
R
A
S
G
P
D
G
A
T
G
Chimpanzee
Pan troglodytes
XP_510426
221
24917
N56
K
R
V
V
Y
R
A
N
G
P
D
G
A
I
G
Rhesus Macaque
Macaca mulatta
XP_001089307
221
24877
N56
K
R
V
V
Y
R
A
N
G
P
D
G
A
I
G
Dog
Lupus familis
XP_541092
256
28618
Q94
K
R
V
V
Y
N
T
Q
G
P
N
G
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERI2
221
24999
N56
K
R
V
V
Y
R
A
N
G
P
D
G
A
V
G
Rat
Rattus norvegicus
P23640
221
25050
N56
K
R
V
V
Y
R
A
N
G
P
D
G
T
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509953
315
35118
R153
K
R
V
V
Y
N
S
R
G
P
N
G
S
P
G
Chicken
Gallus gallus
Q5F470
207
23503
I57
I
E
L
D
G
K
R
I
K
L
Q
I
W
D
T
Frog
Xenopus laevis
NP_001087958
221
25021
N56
K
R
V
V
Y
R
S
N
G
P
D
G
N
T
G
Zebra Danio
Brachydanio rerio
NP_001025428
222
25064
S56
K
R
V
V
Y
K
S
S
G
P
D
G
T
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25228
220
24843
F58
V
S
T
V
G
I
D
F
K
V
K
T
V
F
R
Honey Bee
Apis mellifera
XP_394733
208
24017
T57
Y
Q
T
A
N
G
R
T
Q
R
V
H
L
Q
L
Nematode Worm
Caenorhab. elegans
Q94986
219
24741
F59
V
S
T
V
G
I
D
F
K
V
K
T
V
F
R
Sea Urchin
Strong. purpuratus
XP_001190480
289
32303
K123
K
R
V
T
H
R
P
K
G
A
D
P
T
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28186
216
23816
K62
R
T
I
E
L
D
G
K
R
I
K
L
Q
I
W
Baker's Yeast
Sacchar. cerevisiae
P07560
215
23487
F57
I
T
T
I
G
I
D
F
K
I
K
T
V
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.7
61.3
N.A.
95.9
96.3
N.A.
49.5
40.7
88.6
83.3
N.A.
42.9
64.7
41.1
56.4
Protein Similarity:
100
99.5
98.6
71.8
N.A.
96.3
96.8
N.A.
58.7
61
96.3
90
N.A.
64.7
79.1
65.1
64
P-Site Identity:
100
86.6
86.6
60
N.A.
86.6
80
N.A.
60
0
80
73.3
N.A.
6.6
0
6.6
46.6
P-Site Similarity:
100
93.3
93.3
80
N.A.
93.3
86.6
N.A.
80
13.3
93.3
86.6
N.A.
6.6
13.3
6.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.5
40.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.8
64.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
32
0
0
7
0
0
25
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
7
19
0
0
0
50
0
0
13
0
% D
% Glu:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
25
7
7
0
63
0
0
57
0
0
57
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
13
0
7
7
0
19
0
7
0
13
0
7
0
19
7
% I
% Lys:
63
0
0
0
0
13
0
13
25
0
25
0
0
0
0
% K
% Leu:
0
0
7
0
7
0
0
0
0
7
0
7
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
13
0
32
0
0
13
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
57
0
7
0
7
0
% P
% Gln:
0
7
0
0
0
0
0
7
7
0
7
0
7
7
0
% Q
% Arg:
7
63
0
0
0
44
13
7
7
7
0
0
0
0
19
% R
% Ser:
0
13
0
0
0
0
19
13
0
0
0
0
13
7
0
% S
% Thr:
0
13
25
7
0
0
7
7
0
0
0
19
19
19
7
% T
% Val:
13
0
63
69
0
0
0
0
0
13
7
0
19
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% W
% Tyr:
7
0
0
0
57
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _