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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASCL1
All Species:
21.52
Human Site:
S81
Identified Species:
47.33
UniProt:
P50553
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50553
NP_004307.2
236
25454
S81
P
S
G
G
G
H
K
S
A
P
K
Q
V
K
R
Chimpanzee
Pan troglodytes
XP_521719
193
20195
A53
G
G
G
A
A
A
V
A
R
R
N
E
R
E
R
Rhesus Macaque
Macaca mulatta
XP_001094978
238
25630
S83
P
S
G
G
G
H
K
S
A
P
K
Q
V
K
R
Dog
Lupus familis
XP_539745
369
40138
S214
P
S
G
G
G
H
K
S
A
S
K
Q
V
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q02067
231
24737
S76
P
S
G
G
G
H
K
S
A
A
K
Q
D
K
R
Rat
Rattus norvegicus
P19359
233
24953
S78
P
S
G
G
G
H
K
S
A
A
K
Q
V
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506820
235
25615
S80
P
S
G
G
G
H
K
S
A
P
K
Q
V
K
R
Chicken
Gallus gallus
Q90690
216
24388
D75
A
N
G
A
P
G
M
D
H
S
H
Y
G
G
V
Frog
Xenopus laevis
Q06234
199
22356
L59
Q
R
S
A
S
P
E
L
M
R
C
K
R
R
L
Zebra Danio
Brachydanio rerio
Q90259
196
21910
L56
Q
R
S
S
S
P
E
L
L
R
C
K
R
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797956
185
20703
N45
R
V
R
R
L
R
V
N
D
E
E
T
P
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
98.3
56.6
N.A.
93.2
96.1
N.A.
88.9
23.7
69.4
72.4
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
39.4
98.3
57.7
N.A.
93.6
96.1
N.A.
89.8
34.3
74.1
76.2
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
13.3
100
93.3
N.A.
86.6
93.3
N.A.
100
6.6
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
100
93.3
N.A.
86.6
93.3
N.A.
100
13.3
20
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
28
10
10
0
10
55
19
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
19
0
0
10
10
10
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
73
55
55
10
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
55
0
0
10
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
55
0
0
0
55
19
0
55
0
% K
% Leu:
0
0
0
0
10
0
0
19
10
0
0
0
0
0
28
% L
% Met:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
55
0
0
0
10
19
0
0
0
28
0
0
10
0
0
% P
% Gln:
19
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% Q
% Arg:
10
19
10
10
0
10
0
0
10
28
0
0
28
19
64
% R
% Ser:
0
55
19
10
19
0
0
55
0
19
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
10
0
0
0
0
19
0
0
0
0
0
46
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _