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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASCL1
All Species:
23.94
Human Site:
S223
Identified Species:
52.67
UniProt:
P50553
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50553
NP_004307.2
236
25454
S223
E
G
S
Y
D
P
L
S
P
E
E
Q
E
L
L
Chimpanzee
Pan troglodytes
XP_521719
193
20195
R181
G
A
L
S
P
A
E
R
E
L
L
D
F
S
S
Rhesus Macaque
Macaca mulatta
XP_001094978
238
25630
S225
E
G
S
Y
D
P
L
S
P
E
E
Q
E
L
L
Dog
Lupus familis
XP_539745
369
40138
S356
E
G
S
Y
D
P
L
S
P
E
E
Q
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q02067
231
24737
S218
E
G
S
Y
D
P
L
S
P
E
E
Q
E
L
L
Rat
Rattus norvegicus
P19359
233
24953
S220
E
G
S
Y
D
P
L
S
P
E
E
Q
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506820
235
25615
S222
E
G
S
Y
D
P
L
S
P
E
E
Q
E
L
L
Chicken
Gallus gallus
Q90690
216
24388
T203
D
K
K
T
K
G
R
T
G
W
P
Q
H
V
W
Frog
Xenopus laevis
Q06234
199
22356
P187
G
S
Y
D
P
L
S
P
E
E
Q
E
L
L
D
Zebra Danio
Brachydanio rerio
Q90259
196
21910
P184
G
S
Y
D
P
L
S
P
E
E
Q
E
L
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797956
185
20703
P173
S
P
C
E
P
L
S
P
E
D
E
D
L
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
98.3
56.6
N.A.
93.2
96.1
N.A.
88.9
23.7
69.4
72.4
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
39.4
98.3
57.7
N.A.
93.6
96.1
N.A.
89.8
34.3
74.1
76.2
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
100
26.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
19
55
0
0
0
0
10
0
19
0
0
19
% D
% Glu:
55
0
0
10
0
0
10
0
37
73
64
19
55
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
28
55
0
0
0
10
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
28
55
0
0
10
10
0
28
82
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
10
0
0
37
55
0
28
55
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
19
64
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% R
% Ser:
10
19
55
10
0
0
28
55
0
0
0
0
0
10
10
% S
% Thr:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% W
% Tyr:
0
0
19
55
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _