Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASCL1 All Species: 24.24
Human Site: S214 Identified Species: 53.33
UniProt: P50553 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50553 NP_004307.2 236 25454 S214 S P V S S Y S S D E G S Y D P
Chimpanzee Pan troglodytes XP_521719 193 20195 C172 Y S S D D S G C E G A L S P A
Rhesus Macaque Macaca mulatta XP_001094978 238 25630 S216 S P V S S Y S S D E G S Y D P
Dog Lupus familis XP_539745 369 40138 S347 S P V S S Y S S D E G S Y D P
Cat Felis silvestris
Mouse Mus musculus Q02067 231 24737 S209 S P V S S Y S S D E G S Y D P
Rat Rattus norvegicus P19359 233 24953 S211 S P V S S Y S S D E G S Y D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506820 235 25615 S213 S P V S S Y S S D E G S Y D P
Chicken Gallus gallus Q90690 216 24388 S194 I L K S T V S S S D K K T K G
Frog Xenopus laevis Q06234 199 22356 D178 P V S S Y S S D E G S Y D P L
Zebra Danio Brachydanio rerio Q90259 196 21910 D175 P V S S Y S S D E G S Y D P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797956 185 20703 G164 S P A S S P G G S S P C E P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.8 98.3 56.6 N.A. 93.2 96.1 N.A. 88.9 23.7 69.4 72.4 N.A. N.A. N.A. N.A. 41.9
Protein Similarity: 100 39.4 98.3 57.7 N.A. 93.6 96.1 N.A. 89.8 34.3 74.1 76.2 N.A. N.A. N.A. N.A. 50.4
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 20 13.3 13.3 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 100 33.3 20 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 10 10 0 0 19 55 10 0 0 19 55 0 % D
% Glu: 0 0 0 0 0 0 0 0 28 55 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 19 10 0 28 55 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 10 10 0 10 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 28 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 64 0 0 0 10 0 0 0 0 10 0 0 37 55 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 64 10 28 91 64 28 82 64 19 10 19 55 10 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 19 55 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 19 55 0 0 0 0 0 19 55 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _