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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASCL1
All Species:
22.73
Human Site:
S106
Identified Species:
50
UniProt:
P50553
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50553
NP_004307.2
236
25454
S106
C
K
R
R
L
N
F
S
G
F
G
Y
S
L
P
Chimpanzee
Pan troglodytes
XP_521719
193
20195
P78
Q
A
L
R
Q
H
V
P
H
G
G
A
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001094978
238
25630
S108
C
K
R
R
L
N
F
S
G
F
G
Y
S
L
P
Dog
Lupus familis
XP_539745
369
40138
S239
C
K
R
R
L
N
F
S
G
F
G
Y
S
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q02067
231
24737
S101
C
K
R
R
L
N
F
S
G
F
G
Y
S
L
P
Rat
Rattus norvegicus
P19359
233
24953
S103
C
K
R
R
L
N
F
S
G
F
G
Y
S
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506820
235
25615
S105
C
K
R
R
L
N
F
S
G
F
G
Y
S
L
P
Chicken
Gallus gallus
Q90690
216
24388
R100
G
P
R
P
V
K
R
R
G
T
A
N
R
K
E
Frog
Xenopus laevis
Q06234
199
22356
A84
Q
Q
Q
P
A
A
V
A
R
R
N
E
R
E
R
Zebra Danio
Brachydanio rerio
Q90259
196
21910
A81
Q
Q
Q
P
H
A
V
A
R
R
N
E
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797956
185
20703
Q70
H
L
G
Y
E
L
N
Q
P
A
P
A
A
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
98.3
56.6
N.A.
93.2
96.1
N.A.
88.9
23.7
69.4
72.4
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
39.4
98.3
57.7
N.A.
93.6
96.1
N.A.
89.8
34.3
74.1
76.2
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
100
13.3
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
20
20
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
19
0
19
0
10
10
19
10
0
10
% A
% Cys:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
19
0
19
10
% E
% Phe:
0
0
0
0
0
0
55
0
0
55
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
0
64
10
64
0
0
0
0
% G
% His:
10
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
55
0
0
0
10
0
0
0
0
0
0
0
19
10
% K
% Leu:
0
10
10
0
55
10
0
0
0
0
0
0
0
55
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
55
10
0
0
0
19
10
0
0
0
% N
% Pro:
0
10
0
28
0
0
0
10
10
0
10
0
0
0
55
% P
% Gln:
28
19
19
0
10
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
64
64
0
0
10
10
19
19
0
0
28
0
19
% R
% Ser:
0
0
0
0
0
0
0
55
0
0
0
0
64
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
28
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
55
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _