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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNAQ
All Species:
27.27
Human Site:
S65
Identified Species:
60
UniProt:
P50148
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50148
NP_002063.2
359
42142
S65
Q
M
R
I
I
H
G
S
G
Y
S
D
E
D
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117841
394
45986
A65
Q
M
R
I
I
H
G
A
G
Y
S
E
E
D
K
Dog
Lupus familis
XP_533951
359
42087
A65
Q
M
R
I
I
H
G
A
G
Y
S
E
E
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P21279
359
42140
S65
Q
M
R
I
I
H
G
S
G
Y
S
D
E
D
K
Rat
Rattus norvegicus
P82471
359
42126
S65
Q
M
R
I
I
H
G
S
G
Y
S
D
E
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P50146
354
40360
A59
Q
M
K
I
I
H
E
A
G
Y
S
E
E
E
C
Frog
Xenopus laevis
P38410
359
42198
S65
Q
M
R
I
I
H
G
S
G
Y
S
D
E
D
K
Zebra Danio
Brachydanio rerio
NP_001138271
359
42137
S65
Q
M
R
I
I
H
G
S
G
Y
S
E
E
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23625
353
41277
S59
Q
M
R
I
I
H
G
S
G
Y
S
D
E
D
K
Honey Bee
Apis mellifera
XP_623211
353
41539
S59
Q
M
R
I
I
H
G
S
G
Y
S
D
D
D
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999835
353
41368
A59
Q
M
R
I
I
H
G
A
G
Y
T
E
E
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
81.9
89.9
N.A.
99.7
99.4
N.A.
N.A.
51.8
96.6
92.7
N.A.
76
83
N.A.
82.1
Protein Similarity:
100
N.A.
87.5
96.3
N.A.
100
100
N.A.
N.A.
65.1
98.3
97.4
N.A.
86
89.4
N.A.
89.6
P-Site Identity:
100
N.A.
86.6
86.6
N.A.
100
100
N.A.
N.A.
60
100
86.6
N.A.
100
93.3
N.A.
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
100
100
N.A.
100
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
55
10
91
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
46
91
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
91
0
100
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
100
100
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
73
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
91
0
0
0
0
0
0
0
0
0
0
0
19
% R
% Ser:
0
0
0
0
0
0
0
64
0
0
91
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _