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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNMT
All Species:
14.24
Human Site:
T205
Identified Species:
31.33
UniProt:
P50135
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50135
NP_008826.1
292
33295
T205
Y
I
T
S
D
D
L
T
Q
M
L
D
N
L
G
Chimpanzee
Pan troglodytes
XP_001155975
292
33249
T205
Y
I
T
S
D
D
L
T
Q
M
L
D
N
L
G
Rhesus Macaque
Macaca mulatta
XP_001094746
292
33293
T205
Y
V
T
S
D
D
I
T
Q
M
L
D
N
L
G
Dog
Lupus familis
XP_533340
292
33548
T205
Y
V
T
S
S
D
L
T
Q
M
L
D
K
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91VF2
295
33646
A206
Y
V
T
S
S
D
L
A
Q
I
L
D
D
L
G
Rat
Rattus norvegicus
Q01984
295
33923
A206
Y
V
T
S
S
D
L
A
Q
I
L
D
D
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510925
320
35175
A233
Y
I
S
A
A
D
V
A
A
A
L
D
A
G
G
Chicken
Gallus gallus
XP_422143
292
32869
K205
Y
V
S
S
A
N
I
K
G
I
L
D
S
V
G
Frog
Xenopus laevis
Q5U4V2
293
33067
A205
Y
I
T
A
G
D
I
A
E
M
L
S
S
M
G
Zebra Danio
Brachydanio rerio
Q6DC37
292
33600
K205
C
V
T
I
G
E
I
K
S
F
L
D
S
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786900
298
33811
S207
C
T
T
H
L
R
D
S
L
S
S
L
D
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
92.4
87.6
N.A.
83
83.3
N.A.
49.3
59.9
59
43.8
N.A.
N.A.
N.A.
N.A.
31.5
Protein Similarity:
100
99.6
95.5
93.1
N.A.
92.5
91.5
N.A.
67.8
79.4
78.5
66.7
N.A.
N.A.
N.A.
N.A.
58.3
P-Site Identity:
100
100
86.6
80
N.A.
66.6
66.6
N.A.
40
33.3
46.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
60
80
80
53.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
19
0
0
37
10
10
0
0
10
0
0
% A
% Cys:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
28
73
10
0
0
0
0
82
28
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
19
0
0
0
10
0
0
0
0
10
91
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
37
0
10
0
0
37
0
0
28
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
19
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
10
0
46
0
10
0
91
10
0
55
0
% L
% Met:
0
0
0
0
0
0
0
0
0
46
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
28
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
55
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
19
64
28
0
0
10
10
10
10
10
28
0
0
% S
% Thr:
0
10
82
0
0
0
0
37
0
0
0
0
0
0
0
% T
% Val:
0
55
0
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _