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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD1
All Species:
26.67
Human Site:
Y287
Identified Species:
58.67
UniProt:
P49961
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49961
NP_001091645.1
510
57965
Y287
D
P
C
F
H
P
G
Y
K
K
V
V
N
V
S
Chimpanzee
Pan troglodytes
XP_001140109
495
53927
Q279
P
C
Y
L
S
G
Y
Q
T
T
L
A
L
G
P
Rhesus Macaque
Macaca mulatta
XP_001100060
510
57888
Y287
D
P
C
F
H
P
G
Y
K
K
V
G
N
V
S
Dog
Lupus familis
XP_543939
528
60168
Y305
D
P
C
F
H
P
G
Y
E
T
V
M
N
V
S
Cat
Felis silvestris
Mouse
Mus musculus
P55772
510
57187
Y286
D
P
C
F
N
P
G
Y
E
K
V
V
N
V
S
Rat
Rattus norvegicus
P97687
511
57389
Y286
D
P
C
F
Y
P
G
Y
K
K
V
V
N
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509821
515
57743
T282
C
Y
P
R
D
Y
E
T
D
F
K
M
K
H
T
Chicken
Gallus gallus
O93295
493
54016
Y277
H
P
C
Y
P
K
G
Y
R
R
I
I
T
I
A
Frog
Xenopus laevis
NP_001085737
508
57031
Y285
D
P
C
F
N
S
G
Y
R
R
N
T
S
T
S
Zebra Danio
Brachydanio rerio
NP_001003545
492
55489
T276
F
H
P
G
Y
N
T
T
K
T
L
E
S
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18411
485
54291
N269
L
I
G
E
F
T
V
N
G
T
G
E
W
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
98
74.4
N.A.
76.2
74.3
N.A.
39.4
41.9
55.4
52.1
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.2
99
85
N.A.
86.4
85.7
N.A.
58.4
58.8
72.9
69
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
100
0
93.3
80
N.A.
86.6
93.3
N.A.
0
26.6
46.6
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
6.6
93.3
93.3
N.A.
100
100
N.A.
13.3
73.3
73.3
40
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
10
10
64
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
0
0
0
10
0
0
0
10
0
0
0
0
10
0
% D
% Glu:
0
0
0
10
0
0
10
0
19
0
0
19
0
0
0
% E
% Phe:
10
0
0
55
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
10
64
0
10
0
10
10
0
10
0
% G
% His:
10
10
0
0
28
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
10
10
0
10
0
% I
% Lys:
0
0
0
0
0
10
0
0
37
37
10
0
10
0
0
% K
% Leu:
10
0
0
10
0
0
0
0
0
0
19
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% M
% Asn:
0
0
0
0
19
10
0
10
0
0
10
0
46
0
10
% N
% Pro:
10
64
19
0
10
46
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
19
19
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
10
0
0
0
0
0
0
19
0
55
% S
% Thr:
0
0
0
0
0
10
10
19
10
37
0
10
10
10
10
% T
% Val:
0
0
0
0
0
0
10
0
0
0
46
28
0
55
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
10
10
10
19
10
10
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _