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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG4
All Species:
17.88
Human Site:
S779
Identified Species:
28.1
UniProt:
P49917
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49917
NP_001091738.1
911
103971
S779
N
Q
L
K
E
V
F
S
G
I
K
N
S
N
E
Chimpanzee
Pan troglodytes
XP_509726
911
103942
S779
N
Q
L
K
E
V
F
S
G
I
K
N
S
N
E
Rhesus Macaque
Macaca mulatta
XP_001084107
642
73046
E514
G
S
G
C
T
M
K
E
L
Y
D
L
G
L
K
Dog
Lupus familis
XP_542663
911
104163
S779
N
Q
L
K
E
V
F
S
G
I
K
N
S
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTF7
911
104067
L779
D
Q
L
K
E
V
F
L
G
I
K
P
S
E
Q
Rat
Rattus norvegicus
NP_001099565
911
104477
L779
D
Q
L
K
E
V
F
L
R
I
K
P
S
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YB1
912
104431
S784
A
Q
L
K
E
V
F
S
R
V
K
D
N
K
K
Frog
Xenopus laevis
NP_001081114
911
104084
H782
Y
P
L
R
D
V
F
H
R
M
S
K
I
K
E
Zebra Danio
Brachydanio rerio
NP_001096593
909
103624
V781
S
E
Q
Q
L
R
D
V
I
E
R
I
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572907
918
104813
E790
K
D
I
A
N
V
E
E
L
Q
D
L
L
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188102
952
108709
A817
E
K
L
R
E
V
F
A
N
V
E
K
K
K
S
Poplar Tree
Populus trichocarpa
XP_002325262
1242
139306
S784
S
D
I
K
Q
L
L
S
N
I
N
A
S
E
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LL84
1219
137833
S775
E
G
L
K
Q
V
L
S
N
A
K
Q
S
E
D
Baker's Yeast
Sacchar. cerevisiae
Q08387
944
108496
K816
T
K
L
S
S
L
Y
K
S
Q
L
S
L
P
P
Red Bread Mold
Neurospora crassa
Q7SB49
1046
118891
D865
E
E
A
E
Q
A
V
D
K
F
G
D
S
Y
A
Conservation
Percent
Protein Identity:
100
99.4
68.9
91
N.A.
86.9
86.1
N.A.
N.A.
76.5
72.5
64.1
N.A.
29.7
N.A.
N.A.
48.5
Protein Similarity:
100
99.7
69.8
95.5
N.A.
92.5
92
N.A.
N.A.
87.1
84
79.3
N.A.
51.3
N.A.
N.A.
65.4
P-Site Identity:
100
100
0
86.6
N.A.
66.6
60
N.A.
N.A.
53.3
26.6
6.6
N.A.
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
100
13.3
100
N.A.
80
73.3
N.A.
N.A.
80
46.6
40
N.A.
13.3
N.A.
N.A.
60
Percent
Protein Identity:
27.2
N.A.
N.A.
27.6
25.5
29.2
Protein Similarity:
43.3
N.A.
N.A.
44.9
46.9
47.2
P-Site Identity:
26.6
N.A.
N.A.
40
6.6
6.6
P-Site Similarity:
60
N.A.
N.A.
53.3
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
0
7
0
7
0
7
0
7
0
0
14
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
14
0
0
7
0
7
7
0
0
14
14
0
0
14
% D
% Glu:
20
14
0
7
47
0
7
14
0
7
7
0
0
27
20
% E
% Phe:
0
0
0
0
0
0
54
0
0
7
0
0
0
0
0
% F
% Gly:
7
7
7
0
0
0
0
0
27
0
7
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
14
0
0
0
0
0
7
40
0
7
7
0
0
% I
% Lys:
7
14
0
54
0
0
7
7
7
0
47
14
7
20
20
% K
% Leu:
0
0
67
0
7
14
14
14
14
0
7
14
14
7
0
% L
% Met:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% M
% Asn:
20
0
0
0
7
0
0
0
20
0
7
20
7
14
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
14
0
7
7
% P
% Gln:
0
40
7
7
20
0
0
0
0
14
0
7
0
7
14
% Q
% Arg:
0
0
0
14
0
7
0
0
20
0
7
0
0
0
0
% R
% Ser:
14
7
0
7
7
0
0
40
7
0
7
7
60
14
7
% S
% Thr:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
67
7
7
0
14
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
0
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _