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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG3 All Species: 19.09
Human Site: T479 Identified Species: 35
UniProt: P49916 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49916 NP_002302.2 1009 112907 T479 S V Q A S L M T P V Q P M L A
Chimpanzee Pan troglodytes XP_511409 922 102716 V427 I K Y D G E R V Q V H K N G D
Rhesus Macaque Macaca mulatta XP_001113780 1009 112805 T479 S V Q A S L M T P V Q P M L A
Dog Lupus familis XP_548265 991 110592 T480 S V Q A S L M T P V Q P M L A
Cat Felis silvestris
Mouse Mus musculus P97386 1015 113000 T483 R V Q A S L M T P V Q P M L A
Rat Rattus norvegicus NP_001012011 943 105425 R447 Y E A F K A S R N L Q D V V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006215 902 101303 M407 C K S I E Y A M K K C P N G M
Frog Xenopus laevis NP_001082183 988 110688 T441 S V Q A S L M T P V Q P M L A
Zebra Danio Brachydanio rerio NP_001025345 752 84159 D257 N Q D D M V Q D L E Q G D V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650187 806 90830 K311 L K P V V D H K I R A L K K Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27474 773 86292 R278 G I D E I M R R F R N Q T M T
Sea Urchin Strong. purpuratus XP_786357 875 97201 G380 A N Q K A S N G V P G M T K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P04819 755 84810 T260 M F K P K P L T V G E V F K N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.1 97.7 89.4 N.A. 87.3 82.4 N.A. N.A. 71.3 68.2 55.7 N.A. 34.9 N.A. 23.3 48.4
Protein Similarity: 100 91.1 98.8 92.2 N.A. 91.3 86.4 N.A. N.A. 78.9 79.6 64.9 N.A. 48.1 N.A. 39.3 62.9
P-Site Identity: 100 6.6 100 100 N.A. 93.3 6.6 N.A. N.A. 6.6 100 6.6 N.A. 0 N.A. 0 6.6
P-Site Similarity: 100 6.6 100 100 N.A. 93.3 26.6 N.A. N.A. 6.6 100 33.3 N.A. 0 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 39 8 8 8 0 0 0 8 0 0 0 39 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 16 16 0 8 0 8 0 0 0 8 8 0 8 % D
% Glu: 0 8 0 8 8 8 0 0 0 8 8 0 0 0 8 % E
% Phe: 0 8 0 8 0 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 8 0 0 0 8 0 0 8 0 8 8 8 0 16 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % H
% Ile: 8 8 0 8 8 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 24 8 8 16 0 0 8 8 8 0 8 8 24 8 % K
% Leu: 8 0 0 0 0 39 8 0 8 8 0 8 0 39 0 % L
% Met: 8 0 0 0 8 8 39 8 0 0 0 8 39 8 8 % M
% Asn: 8 8 0 0 0 0 8 0 8 0 8 0 16 0 8 % N
% Pro: 0 0 8 8 0 8 0 0 39 8 0 47 0 0 0 % P
% Gln: 0 8 47 0 0 0 8 0 8 0 54 8 0 0 0 % Q
% Arg: 8 0 0 0 0 0 16 16 0 16 0 0 0 0 0 % R
% Ser: 31 0 8 0 39 8 8 0 0 0 0 0 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 47 0 0 0 0 16 0 8 % T
% Val: 0 39 0 8 8 8 0 8 16 47 0 8 8 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 8 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _