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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK3
All Species:
13.94
Human Site:
Y571
Identified Species:
25.56
UniProt:
P49761
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49761
NP_001123500.1
638
73515
Y571
E
N
S
S
D
G
R
Y
V
K
E
N
C
K
P
Chimpanzee
Pan troglodytes
XP_001136940
490
58560
K432
K
E
N
C
K
P
L
K
S
Y
M
L
Q
D
S
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
Y571
E
N
S
S
D
G
R
Y
V
K
E
N
C
K
P
Dog
Lupus familis
XP_535541
381
44762
K323
K
E
N
C
K
P
L
K
S
Y
M
L
Q
D
S
Cat
Felis silvestris
Mouse
Mus musculus
O35492
638
73779
Y571
E
N
S
S
D
G
R
Y
V
K
E
N
C
K
P
Rat
Rattus norvegicus
Q63117
490
58467
K432
K
E
N
C
K
P
L
K
S
Y
M
L
Q
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012542
490
58745
M432
C
K
P
L
R
T
Y
M
L
H
D
S
L
E
H
Frog
Xenopus laevis
NP_001093358
497
58599
Y439
N
C
H
Q
L
M
S
Y
K
S
G
D
S
P
E
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
S468
P
L
R
R
Y
L
L
S
E
A
E
E
H
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Y750
E
K
S
S
A
G
R
Y
V
R
D
H
C
K
P
Honey Bee
Apis mellifera
XP_395279
439
51412
H381
R
D
N
C
K
P
L
H
R
C
M
L
S
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
R369
W
P
D
G
A
T
S
R
D
S
L
K
A
V
L
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
H594
L
N
S
T
V
I
K
H
F
D
R
K
T
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.6
97.9
59.4
N.A.
88.8
76
N.A.
N.A.
65.8
53.2
51
N.A.
34
43.2
N.A.
N.A.
Protein Similarity:
100
76.6
98.2
59.5
N.A.
89.6
76.3
N.A.
N.A.
70.6
63.4
63.3
N.A.
49.8
53.9
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
100
0
N.A.
N.A.
0
6.6
6.6
N.A.
66.6
0
N.A.
N.A.
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
13.3
N.A.
N.A.
26.6
13.3
6.6
N.A.
86.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
0
0
0
8
0
0
8
0
0
% A
% Cys:
8
8
0
31
0
0
0
0
0
8
0
0
31
0
0
% C
% Asp:
0
8
8
0
24
0
0
0
8
8
16
8
0
31
8
% D
% Glu:
31
24
0
0
0
0
0
0
8
0
31
8
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
31
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
16
0
8
0
8
8
8
8
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
24
16
0
0
31
0
8
24
8
24
0
16
0
31
0
% K
% Leu:
8
8
0
8
8
8
39
0
8
0
8
31
8
8
8
% L
% Met:
0
0
0
0
0
8
0
8
0
0
31
0
0
0
0
% M
% Asn:
8
31
31
0
0
0
0
0
0
0
0
24
0
0
0
% N
% Pro:
8
8
8
0
0
31
0
0
0
0
0
0
0
8
31
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
24
0
8
% Q
% Arg:
8
0
8
8
8
0
31
8
8
8
8
0
0
0
0
% R
% Ser:
0
0
39
31
0
0
16
8
24
16
0
8
16
0
31
% S
% Thr:
0
0
0
8
0
16
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
8
0
0
0
31
0
0
0
0
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
39
0
24
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _