KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK3
All Species:
9.7
Human Site:
Y232
Identified Species:
17.78
UniProt:
P49761
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49761
NP_001123500.1
638
73515
Y232
P
S
F
G
E
D
Y
Y
G
P
S
R
S
R
H
Chimpanzee
Pan troglodytes
XP_001136940
490
58560
Q126
S
S
A
S
S
R
S
Q
Q
S
S
K
R
S
S
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
Y232
P
S
F
G
E
D
Y
Y
G
S
S
R
S
R
H
Dog
Lupus familis
XP_535541
381
44762
Q17
G
R
C
M
Q
R
S
Q
Q
S
S
K
R
S
S
Cat
Felis silvestris
Mouse
Mus musculus
O35492
638
73779
Y232
P
S
F
G
E
D
C
Y
G
S
S
R
S
R
H
Rat
Rattus norvegicus
Q63117
490
58467
Q126
S
S
A
S
S
R
S
Q
Q
S
S
K
R
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012542
490
58745
S126
A
S
S
R
S
Q
Q
S
S
K
R
S
R
S
V
Frog
Xenopus laevis
NP_001093358
497
58599
R133
Y
S
S
S
K
S
Q
R
S
T
K
D
S
Q
N
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
T162
S
S
R
S
D
S
G
T
R
A
L
C
V
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
A376
A
G
G
G
G
G
G
A
A
G
L
Q
Y
D
P
Honey Bee
Apis mellifera
XP_395279
439
51412
P75
D
R
H
R
H
R
S
P
S
S
R
S
Q
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
S63
A
P
S
D
N
S
S
S
L
C
V
K
G
V
A
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
L232
T
G
S
C
A
K
T
L
E
G
N
K
A
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.6
97.9
59.4
N.A.
88.8
76
N.A.
N.A.
65.8
53.2
51
N.A.
34
43.2
N.A.
N.A.
Protein Similarity:
100
76.6
98.2
59.5
N.A.
89.6
76.3
N.A.
N.A.
70.6
63.4
63.3
N.A.
49.8
53.9
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
6.6
N.A.
86.6
13.3
N.A.
N.A.
6.6
13.3
13.3
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
20
93.3
20
N.A.
86.6
20
N.A.
N.A.
6.6
33.3
20
N.A.
13.3
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
16
0
8
0
0
8
8
8
0
0
8
0
8
% A
% Cys:
0
0
8
8
0
0
8
0
0
8
0
8
0
0
0
% C
% Asp:
8
0
0
8
8
24
0
0
0
0
0
8
0
8
8
% D
% Glu:
0
0
0
0
24
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
16
8
31
8
8
16
0
24
16
0
0
8
0
0
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
24
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
8
0
0
0
8
8
39
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
16
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
16
% N
% Pro:
24
8
0
0
0
0
0
8
0
8
0
0
0
0
16
% P
% Gln:
0
0
0
0
8
8
16
24
24
0
0
8
8
8
0
% Q
% Arg:
0
16
8
16
0
31
0
8
8
0
16
24
31
31
0
% R
% Ser:
24
62
31
31
24
24
39
16
24
47
47
16
31
39
24
% S
% Thr:
8
0
0
0
0
0
8
8
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
8
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
16
24
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _