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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK3
All Species:
9.09
Human Site:
S629
Identified Species:
16.67
UniProt:
P49761
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49761
NP_001123500.1
638
73515
S629
G
L
T
P
E
E
R
S
F
H
T
S
R
N
P
Chimpanzee
Pan troglodytes
XP_001136940
490
58560
F482
L
T
P
E
E
R
S
F
H
T
S
R
N
P
S
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
S629
G
L
T
P
E
E
R
S
F
H
T
S
R
N
P
Dog
Lupus familis
XP_535541
381
44762
F373
L
T
P
E
E
R
S
F
H
T
S
R
N
P
S
Cat
Felis silvestris
Mouse
Mus musculus
O35492
638
73779
S629
G
L
T
P
E
E
R
S
F
H
S
S
R
N
P
Rat
Rattus norvegicus
Q63117
490
58467
F482
L
T
P
E
E
R
S
F
H
S
S
R
N
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012542
490
58745
R482
E
E
R
M
L
C
G
R
G
T
S
R
D
L
S
Frog
Xenopus laevis
NP_001093358
497
58599
N489
P
E
E
K
A
L
G
N
R
I
E
R
D
L
S
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
W518
E
L
S
A
G
K
S
W
E
A
N
R
D
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
V808
R
L
P
P
H
H
R
V
G
E
V
S
N
K
Q
Honey Bee
Apis mellifera
XP_395279
439
51412
P431
L
P
A
H
Q
R
L
P
D
L
R
A
A
G
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
R419
I
T
A
R
E
A
L
R
H
P
F
F
A
R
R
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
I729
L
G
I
L
D
D
G
I
A
T
Y
N
N
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.6
97.9
59.4
N.A.
88.8
76
N.A.
N.A.
65.8
53.2
51
N.A.
34
43.2
N.A.
N.A.
Protein Similarity:
100
76.6
98.2
59.5
N.A.
89.6
76.3
N.A.
N.A.
70.6
63.4
63.3
N.A.
49.8
53.9
N.A.
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
93.3
6.6
N.A.
N.A.
0
0
6.6
N.A.
26.6
0
N.A.
N.A.
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
13.3
N.A.
N.A.
6.6
6.6
20
N.A.
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
8
8
0
0
8
8
0
8
16
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
8
0
0
0
24
0
0
% D
% Glu:
16
16
8
24
54
24
0
0
8
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
24
24
0
8
8
0
0
0
% F
% Gly:
24
8
0
0
8
0
24
0
16
0
0
0
0
8
0
% G
% His:
0
0
0
8
8
8
0
0
31
24
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
8
0
8
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
8
0
0
0
0
0
0
0
8
0
% K
% Leu:
39
39
0
8
8
8
16
0
0
8
0
0
0
16
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
8
39
24
0
% N
% Pro:
8
8
31
31
0
0
0
8
0
8
0
0
0
24
24
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
16
% Q
% Arg:
8
0
8
8
0
31
31
16
8
0
8
47
24
8
8
% R
% Ser:
0
0
8
0
0
0
31
24
0
8
39
31
0
0
47
% S
% Thr:
0
31
24
0
0
0
0
0
0
31
16
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _