KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK3
All Species:
9.09
Human Site:
S265
Identified Species:
16.67
UniProt:
P49761
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49761
NP_001123500.1
638
73515
S265
C
H
K
R
R
T
R
S
C
S
S
A
S
S
R
Chimpanzee
Pan troglodytes
XP_001136940
490
58560
V159
L
Q
E
R
Y
E
I
V
G
N
L
G
E
G
T
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
S265
C
H
K
R
R
T
R
S
C
S
S
A
S
S
R
Dog
Lupus familis
XP_535541
381
44762
V50
L
Q
E
R
Y
E
I
V
G
N
L
G
E
G
T
Cat
Felis silvestris
Mouse
Mus musculus
O35492
638
73779
S265
C
H
K
R
R
T
R
S
C
S
S
A
S
S
R
Rat
Rattus norvegicus
Q63117
490
58467
V159
L
Q
E
R
Y
E
I
V
G
N
L
G
E
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012542
490
58745
L159
R
Y
E
I
V
G
S
L
G
E
G
T
F
G
K
Frog
Xenopus laevis
NP_001093358
497
58599
D166
E
R
Y
E
I
V
G
D
L
G
I
G
T
F
G
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
E195
E
I
V
S
T
L
G
E
G
T
F
G
R
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Q409
Q
P
Q
Q
P
Q
Q
Q
Q
Q
Q
Q
Q
S
Q
Honey Bee
Apis mellifera
XP_395279
439
51412
K108
D
I
L
A
N
R
Y
K
V
L
A
T
L
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
P96
E
L
G
D
D
L
T
P
R
Y
K
I
Y
S
K
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
K265
S
L
P
Q
S
N
L
K
K
Q
I
G
S
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.6
97.9
59.4
N.A.
88.8
76
N.A.
N.A.
65.8
53.2
51
N.A.
34
43.2
N.A.
N.A.
Protein Similarity:
100
76.6
98.2
59.5
N.A.
89.6
76.3
N.A.
N.A.
70.6
63.4
63.3
N.A.
49.8
53.9
N.A.
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
100
6.6
N.A.
N.A.
0
0
0
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
20
100
20
N.A.
100
20
N.A.
N.A.
20
6.6
6.6
N.A.
33.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
8
24
0
0
0
% A
% Cys:
24
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
24
0
31
8
0
24
0
8
0
8
0
0
24
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% F
% Gly:
0
0
8
0
0
8
16
0
39
8
8
47
0
39
8
% G
% His:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
8
8
0
24
0
0
0
16
8
0
0
0
% I
% Lys:
0
0
24
0
0
0
0
16
8
0
8
0
0
0
16
% K
% Leu:
24
16
8
0
0
16
8
8
8
8
24
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
8
0
0
0
24
0
0
0
0
0
% N
% Pro:
0
8
8
0
8
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
24
8
16
0
8
8
8
8
16
8
8
8
0
8
% Q
% Arg:
8
8
0
47
24
8
24
0
8
0
0
0
8
0
24
% R
% Ser:
8
0
0
8
8
0
8
24
0
24
24
0
31
47
0
% S
% Thr:
0
0
0
0
8
24
8
0
0
8
0
16
8
0
24
% T
% Val:
0
0
8
0
8
8
0
24
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
24
0
8
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _