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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK3
All Species:
11.82
Human Site:
S135
Identified Species:
21.67
UniProt:
P49761
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49761
NP_001123500.1
638
73515
S135
G
S
G
R
G
A
R
S
G
E
W
G
L
A
A
Chimpanzee
Pan troglodytes
XP_001136940
490
58560
E29
R
R
R
S
Y
S
R
E
H
E
G
R
L
R
Y
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
S135
G
S
G
R
S
A
R
S
G
E
W
G
L
A
A
Dog
Lupus familis
XP_535541
381
44762
Cat
Felis silvestris
Mouse
Mus musculus
O35492
638
73779
S135
G
S
G
R
G
A
R
S
G
E
W
G
L
A
A
Rat
Rattus norvegicus
Q63117
490
58467
E29
R
R
R
S
Y
S
R
E
H
E
G
R
L
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012542
490
58745
A29
R
K
R
S
R
S
R
A
Y
E
G
R
P
R
C
Frog
Xenopus laevis
NP_001093358
497
58599
T36
R
E
G
R
R
L
R
T
H
R
I
S
P
R
A
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
S65
Q
D
T
G
Y
A
R
S
R
S
Y
D
N
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Q279
S
A
S
F
S
S
A
Q
R
P
T
A
L
Q
F
Honey Bee
Apis mellifera
XP_395279
439
51412
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
F135
I
K
E
Q
P
I
Q
F
S
S
P
L
I
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.6
97.9
59.4
N.A.
88.8
76
N.A.
N.A.
65.8
53.2
51
N.A.
34
43.2
N.A.
N.A.
Protein Similarity:
100
76.6
98.2
59.5
N.A.
89.6
76.3
N.A.
N.A.
70.6
63.4
63.3
N.A.
49.8
53.9
N.A.
N.A.
P-Site Identity:
100
20
93.3
0
N.A.
100
20
N.A.
N.A.
13.3
26.6
20
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
26.6
93.3
0
N.A.
100
26.6
N.A.
N.A.
26.6
33.3
33.3
N.A.
20
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
31
8
8
0
0
0
8
0
24
31
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
8
8
0
0
0
0
16
0
47
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
24
0
31
8
16
0
0
0
24
0
24
24
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
0
8
47
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
8
8
0
16
0
8
% P
% Gln:
8
0
0
8
0
0
8
8
0
0
0
0
0
8
0
% Q
% Arg:
31
16
24
31
16
0
62
0
16
8
0
24
0
39
0
% R
% Ser:
8
24
8
24
16
31
0
31
8
16
0
8
0
0
8
% S
% Thr:
0
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% W
% Tyr:
0
0
0
0
24
0
0
0
8
0
8
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _