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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACOT2 All Species: 4.55
Human Site: S7 Identified Species: 10
UniProt: P49753 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49753 NP_006812.3 483 53218 S7 _ M S N K L L S P H P H S V V
Chimpanzee Pan troglodytes XP_510048 483 53239 S7 _ M S N K L L S P H P H S V V
Rhesus Macaque Macaca mulatta XP_001091182 421 46346 L7 _ M S A T L I L E P P G R C C
Dog Lupus familis XP_547892 445 48428 A7 _ M V A S A G A I L R A S G L
Cat Felis silvestris
Mouse Mus musculus Q9QYR9 453 49634 A7 _ M V A S S F A V L R A S R L
Rat Rattus norvegicus O55171 453 49683 A7 _ M V A S S F A V L R A S R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520078 421 46050 L7 _ M A V S L S L Q P S S R C L
Chicken Gallus gallus XP_426429 461 50969 C7 _ M T A F T V C R Q G S R C W
Frog Xenopus laevis NP_001084617 428 46458 P8 M L C L L H R P L A R I L P A
Zebra Danio Brachydanio rerio XP_696711 513 56999 L9 E V N E T G S L E P R F T W Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001169107 421 46466 L7 _ M A A T L S L E P T G R S C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 61.9 75.3 N.A. 68.7 70.1 N.A. 62.9 49.4 52.3 41.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 70.3 81.7 N.A. 79.9 79 N.A. 72.2 62.3 68.1 58.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 28.5 14.2 N.A. 14.2 14.2 N.A. 14.2 7.1 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 35.7 28.5 N.A. 28.5 28.5 N.A. 28.5 21.4 6.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 54.6 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 66.4 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 14.2 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 21.4 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 55 0 10 0 28 0 10 0 28 0 0 10 % A
% Cys: 0 0 10 0 0 0 0 10 0 0 0 0 0 28 19 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 10 0 0 0 0 28 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 19 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 10 10 0 0 0 10 19 0 10 0 % G
% His: 0 0 0 0 0 10 0 0 0 19 0 19 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 10 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 10 10 46 19 37 10 28 0 0 10 0 37 % L
% Met: 10 82 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 19 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 19 37 28 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 10 0 46 0 37 19 0 % R
% Ser: 0 0 28 0 37 19 28 19 0 0 10 19 46 10 0 % S
% Thr: 0 0 10 0 28 10 0 0 0 0 10 0 10 0 0 % T
% Val: 0 10 28 10 0 0 10 0 19 0 0 0 0 19 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _