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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOT2
All Species:
6.67
Human Site:
S24
Identified Species:
14.67
UniProt:
P49753
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49753
NP_006812.3
483
53218
S24
S
E
F
K
M
A
S
S
P
A
V
L
R
A
S
Chimpanzee
Pan troglodytes
XP_510048
483
53239
S24
S
E
F
K
M
A
S
S
P
A
V
L
R
A
S
Rhesus Macaque
Macaca mulatta
XP_001091182
421
46346
R24
E
P
V
R
I
A
V
R
G
L
A
P
E
Q
R
Dog
Lupus familis
XP_547892
445
48428
P24
W
G
F
L
P
R
T
P
K
L
W
A
G
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYR9
453
49634
R24
Q
D
W
K
S
W
A
R
L
F
V
P
P
P
L
Rat
Rattus norvegicus
O55171
453
49683
Q24
W
G
W
K
S
W
T
Q
L
S
G
P
P
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520078
421
46050
R24
E
P
V
R
V
S
V
R
G
L
R
P
G
Q
A
Chicken
Gallus gallus
XP_426429
461
50969
A24
W
L
S
W
P
G
F
A
P
Q
P
L
Q
H
H
Frog
Xenopus laevis
NP_001084617
428
46458
S25
M
S
V
S
M
K
V
S
P
G
H
C
L
I
D
Zebra Danio
Brachydanio rerio
XP_696711
513
56999
S26
D
K
V
I
R
E
L
S
K
A
P
R
H
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169107
421
46466
R24
E
P
L
S
I
T
V
R
G
L
A
P
E
Q
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
61.9
75.3
N.A.
68.7
70.1
N.A.
62.9
49.4
52.3
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
70.3
81.7
N.A.
79.9
79
N.A.
72.2
62.3
68.1
58.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
13.3
N.A.
13.3
6.6
N.A.
0
13.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
33.3
26.6
N.A.
26.6
26.6
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
66.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
28
10
10
0
28
19
10
0
28
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
28
19
0
0
0
10
0
0
0
0
0
0
19
0
0
% E
% Phe:
0
0
28
0
0
0
10
0
0
10
0
0
0
0
0
% F
% Gly:
0
19
0
0
0
10
0
0
28
10
10
0
19
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
10
% H
% Ile:
0
0
0
10
19
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
10
0
37
0
10
0
0
19
0
0
0
0
0
0
% K
% Leu:
0
10
10
10
0
0
10
0
19
37
0
28
10
0
19
% L
% Met:
10
0
0
0
28
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
28
0
0
19
0
0
10
37
0
19
46
19
19
10
% P
% Gln:
10
0
0
0
0
0
0
10
0
10
0
0
10
28
0
% Q
% Arg:
0
0
0
19
10
10
0
37
0
0
10
10
19
10
19
% R
% Ser:
19
10
10
19
19
10
19
37
0
10
0
0
0
0
28
% S
% Thr:
0
0
0
0
0
10
19
0
0
0
0
0
0
0
0
% T
% Val:
0
0
37
0
10
0
37
0
0
0
28
0
0
0
0
% V
% Trp:
28
0
19
10
0
19
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _