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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS3
All Species:
22.12
Human Site:
S186
Identified Species:
60.83
UniProt:
P49746
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49746
NP_009043.1
956
104201
S186
R
M
Q
G
F
V
E
S
M
K
I
I
L
G
G
Chimpanzee
Pan troglodytes
XP_001154764
956
104153
S186
R
M
Q
G
F
V
E
S
M
K
I
I
L
G
G
Rhesus Macaque
Macaca mulatta
XP_001115770
956
104135
S186
R
M
Q
G
F
V
E
S
M
K
I
I
L
G
G
Dog
Lupus familis
XP_537254
956
104099
S186
R
M
Q
G
F
V
E
S
M
K
M
I
L
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q05895
956
103955
S186
R
M
Q
G
F
V
E
S
M
K
I
I
L
G
G
Rat
Rattus norvegicus
P49744
980
108195
E203
K
P
Q
D
F
L
E
E
L
K
L
V
V
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P35440
1178
131798
N166
T
V
Q
V
T
G
E
N
Y
N
L
Y
V
G
C
Frog
Xenopus laevis
Q06441
955
104900
E185
K
G
Q
D
S
M
D
E
L
K
L
V
M
G
G
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
T189
R
M
Q
G
S
M
D
T
L
K
L
A
L
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
97.5
N.A.
96.8
58.2
N.A.
N.A.
36.7
58.7
69.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
99.5
98.7
N.A.
98.2
72.3
N.A.
N.A.
50.1
73.5
82.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
33.3
N.A.
N.A.
20
26.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
N.A.
46.6
73.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
0
23
0
0
23
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
78
23
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
67
0
12
0
0
0
0
0
0
0
89
89
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
45
56
0
0
0
% I
% Lys:
23
0
0
0
0
0
0
0
0
89
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
12
0
0
34
0
45
0
67
0
0
% L
% Met:
0
67
0
0
0
23
0
0
56
0
12
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
67
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% R
% Ser:
0
0
0
0
23
0
0
56
0
0
0
0
0
0
0
% S
% Thr:
12
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
12
0
12
0
56
0
0
0
0
0
23
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _