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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCF All Species: 10
Human Site: T642 Identified Species: 20
UniProt: P49711 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49711 NP_006556.1 727 82785 T642 E P E P Q P V T P A P P P A K
Chimpanzee Pan troglodytes XP_001164059 699 79726 V630 E D E E E P A V E I E P E P E
Rhesus Macaque Macaca mulatta XP_001088665 320 35776 P254 G N M K P P K P T K I K K K G
Dog Lupus familis XP_536815 727 82839 T642 E P E P Q P V T P A P P P A K
Cat Felis silvestris
Mouse Mus musculus Q61164 736 83727 A651 P P P P Q P V A P A P P P A K
Rat Rattus norvegicus Q9R1D1 737 83861 A652 Q P Q P Q P V A P A P P P A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001116829 728 82981 T643 E P E V E P V T P A P P P A K
Chicken Gallus gallus Q08705 728 82810 A643 E P E V S A E A P A P P P S K
Frog Xenopus laevis P08045 1350 155787 S1233 G K K F I D R S S V V K H S R
Zebra Danio Brachydanio rerio NP_001001844 798 89935 V689 L D Q A P P S V P I P A P A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 K695 D P I R Q R I K P A P I I I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 M839 D G E G Q L M M A V P Q G D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.7 43.7 99.5 N.A. 97.9 97.8 N.A. 95 93.4 20.7 72.6 N.A. 27.7 N.A. N.A. 27
Protein Similarity: 100 93.4 44 99.7 N.A. 98.2 98 N.A. 96.5 95 33 78.8 N.A. 43.5 N.A. N.A. 43.2
P-Site Identity: 100 26.6 6.6 100 N.A. 80 80 N.A. 86.6 60 0 33.3 N.A. 33.3 N.A. N.A. 20
P-Site Similarity: 100 40 6.6 100 N.A. 80 93.3 N.A. 93.3 66.6 26.6 46.6 N.A. 46.6 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 9 25 9 59 0 9 0 50 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 17 0 0 0 9 0 0 0 0 0 0 0 9 0 % D
% Glu: 42 0 50 9 17 0 9 0 9 0 9 0 9 0 17 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 9 0 9 0 0 0 0 0 0 0 0 9 0 17 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 9 0 9 0 9 0 0 17 9 9 9 9 0 % I
% Lys: 0 9 9 9 0 0 9 9 0 9 0 17 9 9 50 % K
% Leu: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 9 0 0 0 9 9 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 9 59 9 34 17 67 0 9 67 0 75 59 59 9 0 % P
% Gln: 9 0 17 0 50 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 0 0 0 9 0 9 9 0 0 0 0 0 0 0 9 % R
% Ser: 0 0 0 0 9 0 9 9 9 0 0 0 0 17 0 % S
% Thr: 0 0 0 0 0 0 0 25 9 0 0 0 0 0 0 % T
% Val: 0 0 0 17 0 0 42 17 0 17 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _