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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SARS All Species: 52.12
Human Site: Y168 Identified Species: 81.9
UniProt: P49591 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49591 NP_006504.2 514 58777 Y168 D C T V R K K Y S H V D L V V
Chimpanzee Pan troglodytes XP_001148285 514 58773 Y168 D C T V R K K Y S H V D L V V
Rhesus Macaque Macaca mulatta XP_001089358 498 56983 Y168 D C T V R K K Y S H V D L V V
Dog Lupus familis XP_866214 513 58540 Y167 D C T V R K K Y S H V D L V V
Cat Felis silvestris
Mouse Mus musculus P26638 512 58370 Y168 D C T V R K K Y S H V D L V V
Rat Rattus norvegicus Q6P799 512 58569 Y168 D C T V R K K Y S H V D L V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510792 468 52983 Y122 D C T V R K K Y S H V D L V V
Chicken Gallus gallus NP_001026563 514 58285 Y168 D C S C R K K Y S H V D L V V
Frog Xenopus laevis NP_001080487 510 58328 Y167 D C E V Q K R Y S H V D L V V
Zebra Danio Brachydanio rerio NP_001003882 515 58699 Y168 D C T V Q K K Y S H V D L V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608743 501 56437 Y169 D C E K R G K Y S H V D L I V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18678 487 55201 Y168 D L S T K K K Y S H V D L V V
Sea Urchin Strong. purpuratus XP_793542 526 59300 Y171 D C T V R K K Y S H V D L I H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39230 451 51610 F136 K L W G E K R F S T P G L K L
Baker's Yeast Sacchar. cerevisiae P07284 462 53291 G140 P E D L E A V G P I A S V T G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 83.4 96.1 N.A. 95.5 95.3 N.A. 84.8 85.8 81.7 81.3 N.A. 67.3 N.A. 63 66.5
Protein Similarity: 100 100 87.1 98 N.A. 97.4 98 N.A. 87.3 93.1 89.3 89.5 N.A. 79.9 N.A. 77.6 80.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 80 93.3 N.A. 73.3 N.A. 73.3 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 93.3 100 N.A. 80 N.A. 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 46.8 44.1 N.A.
Protein Similarity: N.A. N.A. N.A. 64.2 58.3 N.A.
P-Site Identity: N.A. N.A. N.A. 20 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % A
% Cys: 0 80 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 87 0 7 0 0 0 0 0 0 0 0 87 0 0 0 % D
% Glu: 0 7 14 0 14 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 7 0 7 0 0 0 7 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 87 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 0 0 0 0 7 0 0 0 14 0 % I
% Lys: 7 0 0 7 7 87 80 0 0 0 0 0 0 7 0 % K
% Leu: 0 14 0 7 0 0 0 0 0 0 0 0 94 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % P
% Gln: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 67 0 14 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 14 0 0 0 0 0 94 0 0 7 0 0 0 % S
% Thr: 0 0 60 7 0 0 0 0 0 7 0 0 0 7 0 % T
% Val: 0 0 0 67 0 0 7 0 0 0 87 0 7 74 80 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 87 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _