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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARS
All Species:
43.03
Human Site:
Y528
Identified Species:
78.89
UniProt:
P49589
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49589
NP_001742.1
748
85473
Y528
L
V
S
Q
C
N
L
Y
M
A
A
R
K
A
V
Chimpanzee
Pan troglodytes
XP_001156397
748
85488
Y528
L
V
S
Q
C
N
L
Y
M
A
A
R
K
A
M
Rhesus Macaque
Macaca mulatta
XP_001096538
748
85443
Y528
L
V
S
Q
C
N
L
Y
M
A
A
R
K
A
M
Dog
Lupus familis
XP_533205
748
85441
Y528
L
V
S
Q
C
N
L
Y
M
A
T
R
K
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER72
831
94841
Y611
L
V
S
Q
C
N
L
Y
M
A
A
R
K
A
E
Rat
Rattus norvegicus
NP_001099789
748
85576
Y528
L
V
S
Q
C
N
L
Y
M
A
A
R
K
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F408
748
85783
Y528
L
V
S
Q
S
N
S
Y
I
A
A
K
K
S
A
Frog
Xenopus laevis
Q7ZWR2
747
85766
Y527
L
V
S
Q
C
N
S
Y
I
A
S
K
K
V
A
Zebra Danio
Brachydanio rerio
NP_001112372
824
93793
Y606
L
V
G
Q
S
N
T
Y
M
A
A
R
R
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN90
741
84240
Y522
L
V
S
V
S
N
V
Y
I
R
D
N
K
T
R
Honey Bee
Apis mellifera
XP_394641
729
84971
Y518
L
V
T
H
C
N
I
Y
M
K
E
I
K
Q
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195853
694
79206
Y518
V
V
N
Q
C
N
V
Y
I
Q
E
R
R
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53852
767
87512
Y549
L
V
T
K
S
N
T
Y
I
T
T
A
G
A
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.4
88.9
N.A.
81.5
89.7
N.A.
N.A.
81.9
76.4
69.9
N.A.
58.9
56.8
N.A.
56.8
Protein Similarity:
100
100
99
94.7
N.A.
87.2
96.1
N.A.
N.A.
91.4
86
78.2
N.A.
71.6
71.9
N.A.
72
P-Site Identity:
100
93.3
93.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
60
60
60
N.A.
40
46.6
N.A.
40
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
80
80
73.3
N.A.
53.3
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
70
54
8
0
54
54
% A
% Cys:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
39
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
0
16
77
0
0
% K
% Leu:
93
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
62
0
0
0
0
0
16
% M
% Asn:
0
0
8
0
0
100
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
77
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
62
16
0
8
% R
% Ser:
0
0
70
0
31
0
16
0
0
0
8
0
0
16
0
% S
% Thr:
0
0
16
0
0
0
16
0
0
8
16
0
0
8
0
% T
% Val:
8
100
0
8
0
0
16
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _