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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARS
All Species:
38.18
Human Site:
Y495
Identified Species:
70
UniProt:
P49589
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49589
NP_001742.1
748
85473
Y495
A
E
L
N
K
N
F
Y
D
K
K
T
A
I
H
Chimpanzee
Pan troglodytes
XP_001156397
748
85488
Y495
A
E
L
N
K
N
F
Y
D
K
K
T
A
I
H
Rhesus Macaque
Macaca mulatta
XP_001096538
748
85443
Y495
A
E
L
N
K
N
F
Y
D
K
K
T
A
I
H
Dog
Lupus familis
XP_533205
748
85441
Y495
S
E
L
N
K
S
F
Y
D
K
K
A
A
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER72
831
94841
Y578
V
E
L
N
K
N
F
Y
G
K
K
T
A
V
H
Rat
Rattus norvegicus
NP_001099789
748
85576
Y495
V
E
L
N
K
N
F
Y
D
K
K
T
A
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F408
748
85783
Y495
A
E
L
N
K
N
F
Y
D
K
K
A
A
I
H
Frog
Xenopus laevis
Q7ZWR2
747
85766
Y494
I
E
L
N
N
C
F
Y
S
K
K
A
A
I
H
Zebra Danio
Brachydanio rerio
NP_001112372
824
93793
Y573
I
E
L
N
K
C
F
Y
D
K
K
T
S
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN90
741
84240
S489
A
A
L
Q
K
K
F
S
N
A
Q
V
Q
V
H
Honey Bee
Apis mellifera
XP_394641
729
84971
Y485
I
E
L
N
E
K
F
Y
N
A
R
D
F
V
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195853
694
79206
L485
I
R
L
N
K
Q
Y
L
E
C
Q
E
K
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53852
767
87512
V516
K
E
L
L
A
D
F
V
E
S
E
S
K
V
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.4
88.9
N.A.
81.5
89.7
N.A.
N.A.
81.9
76.4
69.9
N.A.
58.9
56.8
N.A.
56.8
Protein Similarity:
100
100
99
94.7
N.A.
87.2
96.1
N.A.
N.A.
91.4
86
78.2
N.A.
71.6
71.9
N.A.
72
P-Site Identity:
100
100
100
73.3
N.A.
80
86.6
N.A.
N.A.
93.3
66.6
73.3
N.A.
33.3
40
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
93.3
66.6
86.6
N.A.
53.3
66.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
8
0
0
8
0
0
0
0
16
0
24
62
0
0
% A
% Cys:
0
0
0
0
0
16
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
54
0
0
8
0
0
0
% D
% Glu:
0
85
0
0
8
0
0
0
16
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
93
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% H
% Ile:
31
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% I
% Lys:
8
0
0
0
77
16
0
0
0
70
70
0
16
0
0
% K
% Leu:
0
0
100
8
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
85
8
47
0
0
16
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
0
16
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
0
0
0
8
0
8
8
8
0
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% T
% Val:
16
0
0
0
0
0
0
8
0
0
0
8
0
62
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _