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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARS
All Species:
39.39
Human Site:
S592
Identified Species:
72.22
UniProt:
P49589
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49589
NP_001742.1
748
85473
S592
M
P
Y
L
Q
V
L
S
E
F
R
E
G
V
R
Chimpanzee
Pan troglodytes
XP_001156397
748
85488
S592
M
P
Y
L
Q
V
L
S
E
F
R
E
G
V
R
Rhesus Macaque
Macaca mulatta
XP_001096538
748
85443
S592
M
P
Y
L
Q
V
L
S
E
F
R
E
G
V
R
Dog
Lupus familis
XP_533205
748
85441
S592
M
P
Y
L
Q
V
L
S
E
F
R
E
G
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER72
831
94841
S675
M
P
Y
L
Q
V
L
S
E
F
R
E
G
V
R
Rat
Rattus norvegicus
NP_001099789
748
85576
S592
M
P
Y
L
Q
V
L
S
E
F
R
E
G
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F408
748
85783
S592
M
P
Y
L
Q
V
L
S
E
F
R
E
G
V
R
Frog
Xenopus laevis
Q7ZWR2
747
85766
S591
M
P
Y
L
Q
V
L
S
Q
F
R
E
G
V
R
Zebra Danio
Brachydanio rerio
NP_001112372
824
93793
S670
M
P
Y
L
S
V
L
S
D
F
R
E
D
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN90
741
84240
A588
L
P
Y
V
Q
S
L
A
E
F
R
Y
L
V
R
Honey Bee
Apis mellifera
XP_394641
729
84971
A579
M
P
Y
L
E
I
L
A
N
F
R
E
K
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195853
694
79206
A582
L
P
Y
L
K
V
L
A
E
F
R
Q
T
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53852
767
87512
S613
M
P
Y
V
K
C
L
S
T
F
R
D
D
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.4
88.9
N.A.
81.5
89.7
N.A.
N.A.
81.9
76.4
69.9
N.A.
58.9
56.8
N.A.
56.8
Protein Similarity:
100
100
99
94.7
N.A.
87.2
96.1
N.A.
N.A.
91.4
86
78.2
N.A.
71.6
71.9
N.A.
72
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
80
N.A.
60
66.6
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
86.6
N.A.
80
86.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
8
16
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
70
0
0
77
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
62
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
16
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
16
0
0
85
0
0
100
0
0
0
0
0
8
0
0
% L
% Met:
85
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
70
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
100
% R
% Ser:
0
0
0
0
8
8
0
77
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% T
% Val:
0
0
0
16
0
77
0
0
0
0
0
0
0
93
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
100
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _