KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARS
All Species:
31.21
Human Site:
S278
Identified Species:
57.22
UniProt:
P49589
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49589
NP_001742.1
748
85473
S278
D
T
A
K
F
A
S
S
E
K
H
S
Y
G
K
Chimpanzee
Pan troglodytes
XP_001156397
748
85488
S278
D
T
A
K
F
A
S
S
E
K
H
S
Y
G
K
Rhesus Macaque
Macaca mulatta
XP_001096538
748
85443
S278
D
T
A
K
F
A
S
S
E
K
H
S
Y
G
K
Dog
Lupus familis
XP_533205
748
85441
S278
D
T
V
K
F
A
S
S
E
R
H
S
Y
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER72
831
94841
S361
D
T
A
K
F
A
A
S
E
K
H
S
Y
G
K
Rat
Rattus norvegicus
NP_001099789
748
85576
S278
D
T
A
K
F
A
A
S
E
K
H
S
Y
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F408
748
85783
S278
D
T
V
K
F
G
S
S
E
K
H
S
Y
A
K
Frog
Xenopus laevis
Q7ZWR2
747
85766
S277
S
T
A
K
F
H
D
S
E
N
H
F
Y
A
K
Zebra Danio
Brachydanio rerio
NP_001112372
824
93793
C356
D
T
A
K
F
D
S
C
P
A
H
S
Y
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN90
741
84240
R270
D
V
N
G
F
D
K
R
E
K
H
H
Y
A
K
Honey Bee
Apis mellifera
XP_394641
729
84971
Q268
D
V
S
T
F
N
K
Q
D
K
H
Y
Y
A
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195853
694
79206
D267
T
T
S
K
F
D
N
D
D
S
H
H
Y
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53852
767
87512
S301
D
T
L
K
F
D
K
S
P
N
H
D
Y
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.4
88.9
N.A.
81.5
89.7
N.A.
N.A.
81.9
76.4
69.9
N.A.
58.9
56.8
N.A.
56.8
Protein Similarity:
100
100
99
94.7
N.A.
87.2
96.1
N.A.
N.A.
91.4
86
78.2
N.A.
71.6
71.9
N.A.
72
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
80
60
66.6
N.A.
46.6
40
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
80
60
66.6
N.A.
46.6
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
54
0
0
47
16
0
0
8
0
0
0
54
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
85
0
0
0
0
31
8
8
16
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
100
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
0
0
0
47
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
100
16
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
85
0
0
24
0
0
62
0
0
0
0
100
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
8
0
0
16
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% R
% Ser:
8
0
16
0
0
0
47
70
0
8
0
62
0
0
0
% S
% Thr:
8
85
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
16
16
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
100
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _