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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR109B
All Species:
6.36
Human Site:
S349
Identified Species:
15.56
UniProt:
P49019
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49019
NP_006009.2
387
44496
S349
P
E
A
L
M
A
N
S
G
E
P
W
S
P
S
Chimpanzee
Pan troglodytes
XP_509519
387
44469
S349
P
E
A
L
M
A
N
S
G
E
P
W
S
P
S
Rhesus Macaque
Macaca mulatta
NP_001138726
337
38132
Q301
I
C
S
L
K
P
K
Q
P
G
H
S
K
T
Q
Dog
Lupus familis
XP_543378
363
42072
Q325
P
Q
E
L
D
N
N
Q
S
T
S
M
E
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP66
360
41382
R322
L
G
E
P
D
N
N
R
S
T
S
V
E
L
T
Rat
Rattus norvegicus
Q80Z39
360
41440
T324
E
P
D
N
N
R
S
T
S
V
E
L
T
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506828
616
69877
V581
A
E
P
M
G
D
L
V
L
S
P
P
S
I
S
Chicken
Gallus gallus
P34996
362
41176
L324
G
D
T
F
R
R
R
L
S
R
A
T
R
K
S
Frog
Xenopus laevis
P79928
537
62006
I396
E
W
T
D
T
K
E
I
N
Q
M
M
N
R
R
Zebra Danio
Brachydanio rerio
NP_001156764
328
37733
S290
P
V
V
Y
Y
F
S
S
P
A
V
S
R
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
48.8
79.5
N.A.
74.1
74.9
N.A.
42.3
26.6
22.3
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
63
86.8
N.A.
81.1
81.6
N.A.
48.2
46.5
37.9
55.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
20
N.A.
6.6
0
N.A.
26.6
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
33.3
N.A.
13.3
20
N.A.
33.3
13.3
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
20
0
0
20
0
0
0
10
10
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
10
20
10
0
0
0
0
0
0
0
0
10
% D
% Glu:
20
30
20
0
0
0
10
0
0
20
10
0
20
0
0
% E
% Phe:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
10
0
0
0
20
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
10
10
0
0
0
0
0
10
10
0
% K
% Leu:
10
0
0
40
0
0
10
10
10
0
0
10
0
20
10
% L
% Met:
0
0
0
10
20
0
0
0
0
0
10
20
0
0
0
% M
% Asn:
0
0
0
10
10
20
40
0
10
0
0
0
10
0
0
% N
% Pro:
40
10
10
10
0
10
0
0
20
0
30
10
0
20
0
% P
% Gln:
0
10
0
0
0
0
0
20
0
10
0
0
0
0
10
% Q
% Arg:
0
0
0
0
10
20
10
10
0
10
0
0
20
10
10
% R
% Ser:
0
0
10
0
0
0
20
30
40
10
20
20
30
10
40
% S
% Thr:
0
0
20
0
10
0
0
10
0
20
0
10
10
10
20
% T
% Val:
0
10
10
0
0
0
0
10
0
10
10
10
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
20
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _